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Property, Plant and Equipment Property, Plant and Equipment
6 Months Ended
Jun. 30, 2021
Property, Plant and Equipment [Abstract]  
Property, Plant and Equipment
Property, plant and equipment are recorded at historical cost, net of accumulated depreciation. Accumulated depreciation on property, plant and equipment was $1,880.3 million and $1,782.3 million as of June 30, 2021 and December 31, 2020, respectively. For the three and six months ended June 30, 2021, depreciation expense totaled $54.7 million and $103.5 million, respectively, compared to $51.3 million and $99.7 million, respectively, in the prior year comparative periods.
Solothurn, Switzerland Manufacturing Facility
In order to support our future growth and drug development pipeline, we are building a large-scale biologics manufacturing facility in Solothurn, Switzerland. Upon completion, this facility will include 393,000 square feet related to a large-scale biologics manufacturing facility, 290,000 square feet of warehouse, utilities and support
space and 51,000 square feet of administrative space. As of June 30, 2021 and December 31, 2020, we had approximately $618.4 million and $1.8 billion, respectively, capitalized as construction in progress related to this facility. In the second quarter of 2021, a portion of the facility received a Good Manufacturing Practice multi-product license from the Swiss Agency for Therapeutic Products, resulting in approximately $1.3 billion of fixed assets being placed in service during the second quarter of 2021.