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Fair Value Measurements (Details Textual) - USD ($)	3 Months Ended	6 Months Ended
	Jun. 30, 2021	Jun. 30, 2021	Dec. 31, 2020
Business Acquisition, Contingent Consideration [Line Items]
Asset impairment charges	$ 0	$ 0
Contingent consideration obligations	$ 226,300,000	$ 226,300,000	$ 110,300,000
Technological and Regulatory Success, Probability		21.70%
2.900% Senior Notes due 2020
Business Acquisition, Contingent Consideration [Line Items]
Senior notes interest rate	2.90%	2.90%
3.625% Senior Notes due 2022
Business Acquisition, Contingent Consideration [Line Items]
Senior notes interest rate	3.625%	3.625%
4.050% Senior Notes due 2025
Business Acquisition, Contingent Consideration [Line Items]
Senior notes interest rate	4.05%	4.05%
5.200% Senior Notes due 2045
Business Acquisition, Contingent Consideration [Line Items]
Senior notes interest rate	5.20%	5.20%

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