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Fair Value Measurements (Details Textual) - USD ($) | 3 Months Ended | 9 Months Ended |
--- | --- | --- | ---
Sep. 30, 2021 | Sep. 30, 2021 | Dec. 31, 2020
Business Acquisition, Contingent Consideration [Line Items] |  |  |
Asset impairment charges | $ 0 | $ 0 |
Contingent consideration obligations | $ 210,700,000 | $ 210,700,000 | $ 110,300,000
Technological and Regulatory Success, Probability |  | 10.80% |
3.625% Senior Notes due 2022 |  |  |
Business Acquisition, Contingent Consideration [Line Items] |  |  |
Senior notes interest rate | 3.625% | 3.625% |
4.050% Senior Notes due 2025 |  |  |
Business Acquisition, Contingent Consideration [Line Items] |  |  |
Senior notes interest rate | 4.05% | 4.05% |
5.200% Senior Notes due 2045 |  |  |
Business Acquisition, Contingent Consideration [Line Items] |  |  |
Senior notes interest rate | 5.20% | 5.20% |

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