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Share-Based Payments (Details) - USD ($) $ in Millions | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2021 | Sep. 30, 2020 | Sep. 30, 2021 | Sep. 30, 2020
Share-based Compensation Expense included in consolidated statements of income |  |  |  |
Share-based compensation expense | $ (57.6) | $ (35.4) | $ (186.1) | $ (154.2)
Subtotal | 62.1 | 39.6 | 200.0 | 161.5
Capitalized share-based compensation costs | (1.9) | (1.9) | (6.3) | (4.9)
Share-based compensation expense included in total costs and expenses | 60.2 | 37.7 | 193.7 | 156.6
Income tax effect | (10.9) | (5.4) | (35.8) | (25.7)
Research and development |  |  |  |
Share-based Compensation Expense included in consolidated statements of income |  |  |  |
Share-based compensation expense | 19.5 | 14.6 | 72.2 | 63.1
Selling, general and administrative |  |  |  |
Share-based Compensation Expense included in consolidated statements of income |  |  |  |
Share-based compensation expense | 42.6 | 25.0 | 127.8 | 98.4
Total share-based compensation expense, net of tax |  |  |  |
Share-based Compensation Expense included in consolidated statements of income |  |  |  |
Share-based compensation expense | $ 49.3 | $ 32.3 | $ 157.9 | $ 130.9

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