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Share-Based Payments (Details) - USD ($) $ in Millions | 3 Months Ended
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Mar. 31, 2022 | Mar. 31, 2021
Share-based Compensation Expense included in consolidated statements of income |  |
Share-based compensation expense | $ (70.4) | $ (72.6)
Subtotal | 71.8 | 78.5
Capitalized share-based compensation costs | (2.8) | (2.6)
Share-based compensation expense included in total costs and expenses | 69.0 | 75.9
Income tax effect | (12.8) | (14.0)
Research and development |  |
Share-based Compensation Expense included in consolidated statements of income |  |
Share-based compensation expense | 25.7 | 33.6
Selling, general and administrative |  |
Share-based Compensation Expense included in consolidated statements of income |  |
Share-based compensation expense | 46.1 | 44.9
Total share-based compensation expense, net of tax |  |
Share-based Compensation Expense included in consolidated statements of income |  |
Share-based compensation expense | $ 56.2 | $ 61.9

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