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v3.22.1

Other Consolidated Financial Statement Detail (Details) - USD ($) $ in Millions | 3 Months Ended |
--- | --- | ---
Mar. 31, 2022 | Mar. 31, 2021 | Dec. 31, 2021
Other Income (Expense), Net |  |  |
Interest income | $ 2.9 | $ 2.9 |
Interest expense | (66.1) | (64.7) |
Gains (losses) on investments, net | (191.1) | (436.6) |
Foreign exchange gains (losses), net | (8.3) | (8.6) |
Other, net | (0.7) | 0.1 |
Total other income (expense), net | (263.3) | (506.9) |
Equity Securities, FV-NI, Gain (Loss), Alternative [Abstract] |  |  |
Net gains (losses) recognized during the period on equity securities | (190.7) | (436.1) |
Less: Net gains (losses) realized during the period on equity securities | 0.2 | 6.2 |
Unrealized gains (losses) recognized during the period on equity securities | (190.9) | $ (442.3) |
Accrued Expenses and Other |  |  |
Revenue-related reserves for discounts and allowances | 968.0 |  | $ 935.3
Collaboration expense | 206.6 |  | 345.1
Royalties and licensing fees | 216.0 |  | 234.7
Collaboration expense | 266.2 |  | 324.7
Other | 711.2 |  | 828.6
Total accrued expense and other | 2,231.1 |  | 2,535.2
Ionis, Sangamo, Denali and Sage |  |  |
Equity Securities, FV-NI, Gain (Loss), Alternative [Abstract] |  |  |
Unrealized gains (losses) recognized during the period on equity securities | 205.5 |  |
Component of accrued expenses and other |  |  |
Accrued Expenses and Other |  |  |
Revenue-related reserves for discounts and allowances | $ 831.1 |  | $ 802.1

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