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v3.22.2

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Millions | 6 Months Ended
--- | ---
Jun. 30, 2022 | Jun. 30, 2021
Cash flow from operating activities: |  |
Net income | $ 1,277.2 | $ 1,430.1
Adjustments to reconcile net income to net cash flow from operating activities: |  |
Depreciation and amortization | 277.9 | 219.8
Impairment of intangible assets | 0.0 | 585.9
Excess and obsolescence charges related to inventory | 305.6 | 8.3
Acquired in-process research and development | 0.0 | 18.0
Share-based compensation | 123.3 | 124.1
Contingent consideration | (11.6) | (33.5)
Deferred income taxes | (47.5) | (622.8)
(Gain) loss on strategic investments | 269.3 | 283.6
(Gain) loss on equity method investments | (2.6) | (16.1)
Gain on sale of equity interest in Samsung Bioepis | (1,505.4) | 0.0
Other | 112.2 | 104.1
Changes in operating assets and liabilities, net: |  |
Accounts receivable | (67.3) | 211.5
Due from anti-CD20 therapeutic programs | (23.6) | (8.7)
Inventory | (243.3) | (193.8)
Accrued expense and other current liabilities | 634.0 | (188.4)
Income tax assets and liabilities | (65.9) | 171.5
Other changes in operating assets and liabilities, net | (134.0) | (97.3)
Net cash flow provided by (used in) operating activities | 898.3 | 1,996.3
Cash flows from investing activities: |  |
Purchases of property, plant and equipment | (94.8) | (164.5)
Proceeds from sales and maturities of marketable securities | 1,461.5 | 1,452.7
Purchases of marketable securities | (2,311.6) | (1,626.9)
Proceeds from sale of equity in Samsung Bioepis | (990.3) | 0.0
Proceeds from divestiture of Hillerød, Denmark manufacturing operations | 0.0 | 28.1
Acquisitions of intangible assets | (1.9) | 0.0
Proceeds from the sales of strategic investments | 0.0 | 91.2
Other | 2.0 | 2.0
Net cash flow provided by (used in) investing activities | 45.5 | (217.4)
Cash flows from financing activities: |  |
Purchases of treasury stock | (500.0) | (1,050.0)
Payments related to issuance of stock for share-based compensation arrangements, net | (11.5) | (14.2)
Repayment of borrowings and premiums paid on debt exchange | 0.0 | (170.0)
Net (distribution) contribution to noncontrolling interest | 12.1 | (94.8)
Other | 11.4 | (20.5)
Net cash flow provided by (used in) financing activities | (488.0) | (1,349.5)
Net increase (decrease) in cash and cash equivalents | 455.8 | 429.4
Effect of exchange rate changes on cash and cash equivalents | (70.6) | (18.6)
Cash and cash equivalents, beginning of the period | 2,261.4 | 1,331.2
Cash and cash equivalents, end of the period | $ 2,646.6 | $ 1,742.0

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