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v3.23.1

Other Consolidated Financial Statement Detail (Details) - USD ($) $ in Millions | 3 Months Ended |
--- | --- | ---
Mar. 31, 2023 | Mar. 31, 2022 | Dec. 31, 2022
Other Income (Expense), Net |  |  |
Interest income | $ (80.9) | $ (2.9) |
Interest expense | 62.5 | 66.1 |
(Gains) losses on investments, net | 77.7 | 191.1 |
Foreign exchange (gains) losses, net | 10.7 | 8.3 |
Other, net | (0.6) | 0.7 |
Other (income) expense | 69.4 | 263.3 |
Equity Securities, FV-NI, Gain (Loss), Alternative [Abstract] |  |  |
Net (gains) losses recognized on equity securities | 78.1 | 190.7 |
Less: Net (gains) losses realized on equity securities | 1.6 | (0.2) |
Net unrealized (gains) losses recognized on equity securities | 76.5 | 190.9 |
Accrued Expenses and Other |  |  |
Revenue-related reserves for discounts and allowances | 1,045.0 |  | $ 1,035.0
Collaboration expense | 187.2 |  | 395.6
Royalties and licensing fees | 183.9 |  | 209.4
Collaboration expense | 265.5 |  | 277.9
Other | 744.4 |  | 746.9
Total accrued expense and other | 2,288.2 |  | 2,521.4
Ionis, Sangamo, Denali and Sage |  |  |
Equity Securities, FV-NI, Gain (Loss), Alternative [Abstract] |  |  |
Net unrealized (gains) losses recognized on equity securities | 100.0 | $ 205.5 |
Component of accrued expenses and other |  |  |
Accrued Expenses and Other |  |  |
Revenue-related reserves for discounts and allowances | $ 907.2 |  | $ 891.6

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