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v3.25.1

Insider Trading Arrangements shares in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2025 shares
Trading Arrangements, by Individual |
Material Terms of Trading Arrangement | During the first quarter of 2025 our officers and directors took the following actions with respect to trading arrangements:
|  |  |  |  |  | Trading Arrangement |  |  |  |
Name and Position |  | Action |  | Date |  | Rule 10b5-1 |  | Non-Rule 10b5-1 |  | Total Shares to be Purchased or Sold |  | Expiration Date
Priya Singhal, M.D., EVP, Head of Development |  | Adopt |  | 2/18/2025 |  | X |  | — |  | 19,523 |  | 2/27/2026
Rachid Izzar, EVP, Global Product Strategy and Commercialization |  | Adopt |  | 3/12/2025 |  | X |  | — |  | 2,223 |  | 8/18/2025
Stephen Sherwin, Director |  | Adopt |  | 2/24/2025 |  | X |  | — |  | 4,379 |  | 8/24/2025
Non-Rule 10b5-1 Arrangement Adopted | false
Rule 10b5-1 Arrangement Terminated | false
Non-Rule 10b5-1 Arrangement Terminated | false
Priya Singhal, M.D. [Member] |
Trading Arrangements, by Individual |
Name | Priya Singhal, M.D.
Title | EVP, Head of Development
Rule 10b5-1 Arrangement Adopted | true
Adoption Date | 2/18/2025
Expiration Date | 2/27/2026
Arrangement Duration | 374 days
Aggregate Available | 19,523,000
Rachid Izzar [Member] |
Trading Arrangements, by Individual |
Name | Rachid Izzar
Title | EVP, Global Product Strategy and Commercialization
Rule 10b5-1 Arrangement Adopted | true
Adoption Date | 3/12/2025
Expiration Date | 8/18/2025
Arrangement Duration | 159 days
Aggregate Available | 2,223,000
Stephen Sherwin [Member] |
Trading Arrangements, by Individual |
Name | Stephen Sherwin
Title | Director
Rule 10b5-1 Arrangement Adopted | true
Adoption Date | 2/24/2025
Expiration Date | 8/24/2025
Arrangement Duration | 181 days
Aggregate Available | 4,379,000

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