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Restructuring, Business Transformation and Other Cost Saving Initiatives - Narrative (Details) $ in Millions |  | 3 Months Ended | 6 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | ---
Sep. 26, 2023 USD ($) | Jun. 30, 2025 USD ($) | Jun. 30, 2024 USD ($) | Jun. 30, 2025 USD ($) Employee | Jun. 30, 2024 USD ($) | Mar. 31, 2025 ft² | Sep. 30, 2023 ft² | Jul. 31, 2023 USD ($)
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |
Operating lease area | ft² |  |  |  |  |  | 580,000 |  |
Reata Pharmaceuticals, Inc |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |
Operating lease area | ft² |  |  |  |  |  |  | 327,400 |
Lease term |  |  |  |  |  |  | 16 years |
Minimum |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |
Restructuring and Related Cost, Expected Cost Remaining |  |  |  |  |  |  |  | $ 300.0
Maximum |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |
Restructuring and Related Cost, Expected Cost Remaining |  |  |  |  |  |  |  | $ 310.0
2023 Cost Saving Initiatives |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |
Expected operating expense reduction | $ 1,000.0 |  |  |  |  |  |  |
Expected number of positions eliminated | Employee |  |  |  | 1,400 |  |  |  |
Severance Costs |  | $ (1.1) | $ 6.3 | $ 34.2 | $ 15.6 |  |  |
2023 Cost Saving Initiatives | Restructuring charges |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |
Severance Costs |  | (1.1) | 6.3 | 34.2 | 15.6 |  |  |
Reata Integration |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |
Severance Costs |  | 0.0 | 0.3 | (0.2) | 2.5 |  |  |
Reata Integration | Minimum |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |
Expected cost |  | 35.0 |  | 35.0 |  |  |  |
Reata Integration | Restructuring charges |  |  |  |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |  |  |  |
Severance Costs |  | $ 0.0 | $ 0.3 | $ (0.2) | $ 2.5 |  |  |

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