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v3.25.2

Collaborative and Other Relationships - Other Research and Discovery Arrangements and Funding Arrangements (Details) - USD ($) $ in Millions | 3 Months Ended | 6 Months Ended |
--- | --- | --- | ---
Jun. 30, 2025 | Jun. 30, 2025 | Feb. 11, 2025
Collaborative arrangements and non-collaborative arrangement transactions |  |  |
Reduction of research and development expense | $ 50.0 | $ 100.0 |
Milestone Payment, Future Development |  |  |
Collaborative arrangements and non-collaborative arrangement transactions |  |  |
Estimated additional payments upon achievement of development and commercial milestones | 250.0 | 250.0 |
Felzartamab And Izastobart/HIB210 | Human Immunology Biosciences Pre-Existing In License Commitments | Milestone Payment, One |  |  |
Collaborative arrangements and non-collaborative arrangement transactions |  |  |
Estimated additional payments upon achievement of development and commercial milestones | 35.0 | 35.0 |
Felzartamab And Izastobart/HIB210 | Human Immunology Biosciences Pre-Existing In License Commitments | Milestone Payment, Two |  |  |
Collaborative arrangements and non-collaborative arrangement transactions |  |  |
Estimated additional payments upon achievement of development and commercial milestones | 30.0 | 30.0 |
Felzartamab And Izastobart/HIB210 | Human Immunology Biosciences Pre-Existing In License Commitments | Milestone Payment, Future Development |  |  |
Collaborative arrangements and non-collaborative arrangement transactions |  |  |
Estimated additional payments upon achievement of development and commercial milestones | 130.0 | 130.0 |
Felzartamab And Izastobart/HIB210 | Human Immunology Biosciences Pre-Existing In License Commitments | Milestone Payment, Regulatory |  |  |
Collaborative arrangements and non-collaborative arrangement transactions |  |  |
Estimated additional payments upon achievement of development and commercial milestones | 230.0 | 230.0 |
Felzartamab And Izastobart/HIB210 | Human Immunology Biosciences Pre-Existing In License Commitments | Milestone Payment, Commercial |  |  |
Collaborative arrangements and non-collaborative arrangement transactions |  |  |
Estimated additional payments upon achievement of development and commercial milestones | 640.0 | 640.0 |
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |
Collaborative arrangements and non-collaborative arrangement transactions |  |  |
Expected receipts to co-fund development costs, current |  |  | $ 200.0
Expected receipts to co-fund development costs, noncurrent |  |  | $ 50.0
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | City Therapeutics, Inc. |  |  |
Collaborative arrangements and non-collaborative arrangement transactions |  |  |
Upfront and milestone paymentsmade to collaborative partner | 16.0 | 16.0 |
Collaborative arrangements, investments in counterparty | 30.0 | 30.0 |
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Milestone Payment, Research | City Therapeutics, Inc. |  |  |
Collaborative arrangements and non-collaborative arrangement transactions |  |  |
Estimated additional payments upon achievement of development and commercial milestones | 21.5 | 21.5 |
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Milestone Payment, Developmental | City Therapeutics, Inc. |  |  |
Collaborative arrangements and non-collaborative arrangement transactions |  |  |
Estimated additional payments upon achievement of development and commercial milestones | 360.0 | 360.0 |
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Milestone Payment, Sales-Based | City Therapeutics, Inc. |  |  |
Collaborative arrangements and non-collaborative arrangement transactions |  |  |
Estimated additional payments upon achievement of development and commercial milestones | $ 625.0 | $ 625.0 |

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