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Collaborative and Other Relationships - Sage Therapeutics, Inc. (Details) - USD ($) $ in Millions | 3 Months Ended | 6 Months Ended |
--- | --- | --- | ---
Jun. 30, 2025 | Jun. 30, 2024 | Jun. 30, 2025 | Jun. 30, 2024 | Dec. 31, 2025
Collaborative arrangements and non-collaborative arrangement transactions |  |  |  |  |
Collaboration profit sharing/(loss reimbursement) | $ 75.0 | $ 62.4 | $ 133.1 | $ 128.0 |
Share of net profit from sage therapeutics, Percent | 50.00% |  | 50.00% |  |
Sage Therapeutics |  |  |  |  |
Collaborative arrangements and non-collaborative arrangement transactions |  |  |  |  |
Collaboration profit sharing/(loss reimbursement) | $ 17.8 | $ 6.5 | $ 27.9 | $ 11.5 |
Forecast | Sage Therapeutics |  |  |  |  |
Collaborative arrangements and non-collaborative arrangement transactions |  |  |  |  |
Potential future milestone payments commitment to third party |  |  |  |  | $ 75.0

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