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Income Taxes - Reconciliation of Federal Statutory Rate and Effective Tax Rate (Details)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]      
Tax expense at federal statutory rate (21.00%) (21.00%) (21.00%)
State income taxes, net of federal tax benefit 6.20% 8.70% (364.00%)
Share-based compensation 13.20% 84.10% (2329.40%)
Non-deductible executive compensation 14.30% (7.70%) 86.90%
Research and development credits (25.70%) 40.80% (393.00%)
Other 8.20% (4.90%) (23.20%)
Valuation allowance 7.40% (99.30%) 2827.60%
Effective tax rate 2.60% 0.70% (216.10%)