<SUBMISSION>
<ACCESSION-NUMBER>0001071739-08-000021
<TYPE>8-K
<PUBLIC-DOCUMENT-COUNT>1
<PERIOD>20080714
<ITEMS>5.02
<FILING-DATE>20080715
<DATE-OF-FILING-DATE-CHANGE>20080715
<FILER>
<COMPANY-DATA>
<CONFORMED-NAME>CENTENE CORP
<CIK>0001071739
<ASSIGNED-SIC>6324
<IRS-NUMBER>041406317
</COMPANY-DATA>
<FILING-VALUES>
<FORM-TYPE>8-K
<ACT>34
<FILE-NUMBER>001-31826
<FILM-NUMBER>08952991
</FILING-VALUES>
<BUSINESS-ADDRESS>
<STREET1>7711 CARONDELET AVE
<CITY>ST LOUIS
<STATE>MO
<ZIP>63105
<PHONE>3147254477
</BUSINESS-ADDRESS>
<MAIL-ADDRESS>
<STREET1>7711 CARONDELET AVE
<STREET2>SUITE 800
<CITY>ST LOUIS
<STATE>MO
<ZIP>63105
</MAIL-ADDRESS>
</FILER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>form8k.htm
<DESCRIPTION>FORM 8-K
<TEXT>
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STATES</font></div>
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20549</font>&#160;</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center">&#160;</div>
    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font style="DISPLAY: inline; FONT-WEIGHT: bold">Current
Report</font>&#160;</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font style="DISPLAY: inline; FONT-WEIGHT: bold">Pursuant to Section&#160;13 or 15(d)
of the Securities Exchange Act of 1934</font>&#160;</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="center"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Date
of report (Date of earliest event reported): July 14, 2008</font></div>
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CORPORATION&#160;</font></div>
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appropriate box below if the Form 8-K filing is intended to simultaneously
satisfy the filing obligation of the registrant under any of the following
provisions (see General Instruction A.2. below):</font></div>
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    <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left">
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            <tr valign="top">
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                <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Item
      5.02.</font></div>
              </td>
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                <div align="justify"><font style="DISPLAY: inline; FONT-WEIGHT: bold; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Departure
      of Directors or Certain Officers; Election of Directors; Appointment of
      Certain Officers; Compensatory Arrangements of Certain
      Officers.</font></div>
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      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt; TEXT-ALIGN: left" align="justify">&#160;</div>
      <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt; TEXT-ALIGN: left" align="justify"><font id="TAB2" style="LETTER-SPACING: 9pt">&#160;&#160;&#160;</font>&#160;<font style="FONT-SIZE: 10pt">(e) <font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">On July
14, 2008, we amended our current executive employment agreement with Michael F.
Neidorff, our chairman, president and chief executive officer (&#8220;Employment
Agreement&#8221;) and our form of executive severance and change in control agreement
(&#8220;Severance Agreement&#8221;), which we currently have in place with approximately 70
of our officers, including all of our named executive officers other than Mr.
Neidorff.&#160;&#160;The amendments,&#160;which allow the&#160;Company to
attract and retain employees,&#160;provide that the non-competition and
non-solicitation provisions contained in these agreements, and those in any
equity awards held by these officers, will not apply in the event of a change in
control as described in the first or third bullets below unless the transaction
receives the prior approval, recommendation or consent of the board of
directors, and will also not apply in the event of a change in control as
described in the second bullet below.</font></font>

        <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
        <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font id="TAB2" style="LETTER-SPACING: 9pt">&#160;&#160;&#160;</font>&#160;Generally, a
change in control is deemed to occur under the Employment Agreement and
Severance Agreements:</font></div>
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                <td>
                  <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt; TEXT-ALIGN: left" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">if
      any individual, entity or group (other than a group which includes the
      executive) acquires 40% or more of the voting power of our outstanding
      securities;</font></div>
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                </td>
                <td>
                  <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt; TEXT-ALIGN: left" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">if
      directors constituting a majority of the incumbent board of directors are
      replaced.&#160;&#160;For these purposes, the incumbent board of directors
      means the directors who were serving as of the effective date of the
      applicable agreement and any individual who becomes a director subsequent
      to such date whose election or nomination for election was approved by a
      majority of such directors, other than in connection with a proxy contest;
      or</font></div>
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          </table>
        </div>
        <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
        <div>
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                <td align="right" style="WIDTH: 36pt">
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                <td>
                  <div style="MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt; TEXT-ALIGN: left" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">upon
      the consummation of a merger or consolidation of the Company with another
      person, other than a merger or consolidation where the individuals and
      entities who were beneficial owners, respectively, of our outstanding
      voting securities immediately prior to such merger or consolidation own
      50% or more of the then-outstanding shares of the combined voting power of
      the then-outstanding voting securities of the corporation resulting from
      such merger or consolidation.</font></div>
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        <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="justify">&#160;</div>
        <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt; TEXT-ALIGN: left" align="justify"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman"><font id="TAB2" style="LETTER-SPACING: 9pt">&#160;&#160;&#160;</font>&#160;A description
of the severance benefits for which each of the named executive officers is
eligible upon termination in the event of a change in control can be found under
the section &#8220;Compensation Discussion and Analysis&#8212;Employment Contracts,
Termination of Employment Arrangements, and Change in Control Arrangements&#8221; in
our definitive proxy statement for the 2008 Annual Meeting of Stockholders which
was filed with the SEC on March 10, 2008 and is hereby incorporated by
reference.&#160; One of the severance benefits in the Employment Agreement (an
amount equal to three times base salary plus maximum bonus opportunity) and
Severance Agreements (an amount equal to two times base salary plus the average
cash bonus for the past two years) remains contingent upon the officers
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to the requirements of the Securities Exchange Act of 1934, the Registrant has
duly caused this report to be signed on its behalf by the undersigned hereunto
duly authorized.</font></div>
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      CORPORATION</font></div>
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      July 15, 2008</font></div>
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              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; MARGIN-RIGHT: 0pt" align="left">/s/ Eric R. Slusser</div>
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      R. Slusser</font></div>
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