<SEC-DOCUMENT>0001140361-21-022131-index.html : 20210624
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<ACCEPTANCE-DATETIME>20210624080614
ACCESSION NUMBER:		0001140361-21-022131
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		3
FILED AS OF DATE:		20210624
DATE AS OF CHANGE:		20210624

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CENTENE CORP
		CENTRAL INDEX KEY:			0001071739
		STANDARD INDUSTRIAL CLASSIFICATION:	HOSPITAL & MEDICAL SERVICE PLANS [6324]
		IRS NUMBER:				041406317
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-238050
		FILM NUMBER:		211040623

	BUSINESS ADDRESS:	
		STREET 1:		7700 FORSYTH BLVD.
		CITY:			ST LOUIS
		STATE:			MO
		ZIP:			63105
		BUSINESS PHONE:		3147254477

	MAIL ADDRESS:	
		STREET 1:		7700 FORSYTH BLVD.
		CITY:			ST LOUIS
		STATE:			MO
		ZIP:			63105
</SEC-HEADER>
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<TYPE>424B5
<SEQUENCE>1
<FILENAME>nt10023682x2_424b5.htm
<DESCRIPTION>424B5
<TEXT>
Document 1 - file: nt10023682x2_424b5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>logo_centene.jpg
<TEXT>
Document 2 - file: logo_centene.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>logo_centenex1.jpg
<TEXT>
Document 3 - file: logo_centenex1.jpg

</DOCUMENT>
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