<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2024 Workiva-->
<!--r:c6aa53a5-859d-435a-997a-6f98d0bbbeaf,g:c327a3ff-df02-483d-8601-5b8fe422eee8-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://docusign.com/role/CONDENSEDCONSOLIDATEDBALANCESHEETSUnaudited" xlink:type="simple" xlink:href="docu-20241031.xsd#CONDENSEDCONSOLIDATEDBALANCESHEETSUnaudited"/>
  <link:calculationLink xlink:role="http://docusign.com/role/CONDENSEDCONSOLIDATEDBALANCESHEETSUnaudited" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_a4ee7f8d-b0c5-4420-bbcd-d0276c1b50ed" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockValue_1156b683-0172-40a8-8ca4-0efe43ba193f" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PreferredStockValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_a4ee7f8d-b0c5-4420-bbcd-d0276c1b50ed" xlink:to="loc_us-gaap_PreferredStockValue_1156b683-0172-40a8-8ca4-0efe43ba193f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_3b269d4c-7948-4284-a70d-7b5340885cef" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CommonStockValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_a4ee7f8d-b0c5-4420-bbcd-d0276c1b50ed" xlink:to="loc_us-gaap_CommonStockValue_3b269d4c-7948-4284-a70d-7b5340885cef" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapital_b3f967c4-e4a7-49fc-8359-aed9c5bdae81" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AdditionalPaidInCapital"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_a4ee7f8d-b0c5-4420-bbcd-d0276c1b50ed" xlink:to="loc_us-gaap_AdditionalPaidInCapital_b3f967c4-e4a7-49fc-8359-aed9c5bdae81" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_9d6cfd32-d494-4bb5-b418-ba968f35c9f5" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_a4ee7f8d-b0c5-4420-bbcd-d0276c1b50ed" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_9d6cfd32-d494-4bb5-b418-ba968f35c9f5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_58716c6c-bd46-4646-9d14-fc50d5b0674e" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_a4ee7f8d-b0c5-4420-bbcd-d0276c1b50ed" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_58716c6c-bd46-4646-9d14-fc50d5b0674e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockCommonValue_5b17360f-dcae-4d06-9d93-6a3eca0adc07" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_TreasuryStockCommonValue"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_a4ee7f8d-b0c5-4420-bbcd-d0276c1b50ed" xlink:to="loc_us-gaap_TreasuryStockCommonValue_5b17360f-dcae-4d06-9d93-6a3eca0adc07" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_06cd55f8-966d-4f24-8b49-79400a9373c2" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_ceac9e44-ccda-486f-97e8-4e86e1347578" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_06cd55f8-966d-4f24-8b49-79400a9373c2" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_ceac9e44-ccda-486f-97e8-4e86e1347578" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_f1d41f8c-8b78-4c92-9625-9bd5bf160cad" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_06cd55f8-966d-4f24-8b49-79400a9373c2" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_f1d41f8c-8b78-4c92-9625-9bd5bf160cad" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_68607e60-9672-44f7-981a-022d5aea5c24" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_06cd55f8-966d-4f24-8b49-79400a9373c2" xlink:to="loc_us-gaap_AccountsPayableCurrent_68607e60-9672-44f7-981a-022d5aea5c24" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_e41e6827-92e4-47ba-b1d7-07a250f0291c" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_06cd55f8-966d-4f24-8b49-79400a9373c2" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_e41e6827-92e4-47ba-b1d7-07a250f0291c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityCurrent_8820762d-0ac4-4762-a432-3c3164095b91" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ContractWithCustomerLiabilityCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_06cd55f8-966d-4f24-8b49-79400a9373c2" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityCurrent_8820762d-0ac4-4762-a432-3c3164095b91" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_fbb5ef83-6249-4b5b-a692-316dedca6c4e" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_5d87c259-4b88-4a54-a760-003d2996cbb6" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_Liabilities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_fbb5ef83-6249-4b5b-a692-316dedca6c4e" xlink:to="loc_us-gaap_Liabilities_5d87c259-4b88-4a54-a760-003d2996cbb6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_f1e808a0-9bc3-430c-aeed-5fa01a3ae11f" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_fbb5ef83-6249-4b5b-a692-316dedca6c4e" xlink:to="loc_us-gaap_CommitmentsAndContingencies_f1e808a0-9bc3-430c-aeed-5fa01a3ae11f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_42db6a95-f639-48aa-93cb-15bb19fc7063" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_StockholdersEquity"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_fbb5ef83-6249-4b5b-a692-316dedca6c4e" xlink:to="loc_us-gaap_StockholdersEquity_42db6a95-f639-48aa-93cb-15bb19fc7063" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_3640f840-b3e7-4ea9-bb9f-c0d7337e230f" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AssetsCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterestCurrent_9a23438a-625f-41cf-a4ae-451bed969726" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterestCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_3640f840-b3e7-4ea9-bb9f-c0d7337e230f" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterestCurrent_9a23438a-625f-41cf-a4ae-451bed969726" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_b6cdd9d8-ebd8-466b-ab43-c7fe7056edc5" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_3640f840-b3e7-4ea9-bb9f-c0d7337e230f" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_b6cdd9d8-ebd8-466b-ab43-c7fe7056edc5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_42cb4d3b-995e-4ca3-a3b7-4d7ff22712cc" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_3640f840-b3e7-4ea9-bb9f-c0d7337e230f" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_42cb4d3b-995e-4ca3-a3b7-4d7ff22712cc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerAssetNetCurrent_1c198ffa-7804-4f90-8ba8-b7a265b485f2" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ContractWithCustomerAssetNetCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_3640f840-b3e7-4ea9-bb9f-c0d7337e230f" xlink:to="loc_us-gaap_ContractWithCustomerAssetNetCurrent_1c198ffa-7804-4f90-8ba8-b7a265b485f2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_e148d1e3-cc56-44fd-bb31-ed9ae39de67f" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_3640f840-b3e7-4ea9-bb9f-c0d7337e230f" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_e148d1e3-cc56-44fd-bb31-ed9ae39de67f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_f38d7890-b7ee-4f8d-a607-0f93bc9a2311" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_fdf302eb-d942-4a86-9237-d1138b105210" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AssetsCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_f38d7890-b7ee-4f8d-a607-0f93bc9a2311" xlink:to="loc_us-gaap_AssetsCurrent_fdf302eb-d942-4a86-9237-d1138b105210" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterestNoncurrent_0565489b-c396-4f6b-b28e-5a10ce2063c4" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterestNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_f38d7890-b7ee-4f8d-a607-0f93bc9a2311" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterestNoncurrent_0565489b-c396-4f6b-b28e-5a10ce2063c4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_30c0c21c-aaa0-4e75-9135-7a23f7f3b3e6" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_f38d7890-b7ee-4f8d-a607-0f93bc9a2311" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_30c0c21c-aaa0-4e75-9135-7a23f7f3b3e6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_137e5e5f-2c65-4e5c-8f26-d847b41e03be" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_f38d7890-b7ee-4f8d-a607-0f93bc9a2311" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_137e5e5f-2c65-4e5c-8f26-d847b41e03be" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_89b6d6c3-9385-423a-9388-06033bdf33b7" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_f38d7890-b7ee-4f8d-a607-0f93bc9a2311" xlink:to="loc_us-gaap_Goodwill_89b6d6c3-9385-423a-9388-06033bdf33b7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_f13623a2-8f6d-4074-a5c7-66942f6307fe" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_f38d7890-b7ee-4f8d-a607-0f93bc9a2311" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_f13623a2-8f6d-4074-a5c7-66942f6307fe" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalizedContractCostNetNoncurrent_85674530-4404-4bc4-b805-42e023045918" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CapitalizedContractCostNetNoncurrent"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_f38d7890-b7ee-4f8d-a607-0f93bc9a2311" xlink:to="loc_us-gaap_CapitalizedContractCostNetNoncurrent_85674530-4404-4bc4-b805-42e023045918" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_5d422bb4-675c-49b5-8f1b-3d50c5c45981" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_f38d7890-b7ee-4f8d-a607-0f93bc9a2311" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_5d422bb4-675c-49b5-8f1b-3d50c5c45981" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxAssetsNet_1491b751-3348-4f0c-8121-dcc5a411f4b9" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredIncomeTaxAssetsNet"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_f38d7890-b7ee-4f8d-a607-0f93bc9a2311" xlink:to="loc_us-gaap_DeferredIncomeTaxAssetsNet_1491b751-3348-4f0c-8121-dcc5a411f4b9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_88905f79-a746-4083-b2d5-f862175379de" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_Liabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_ff7183a7-b7d6-4620-812c-71036fb70e34" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_88905f79-a746-4083-b2d5-f862175379de" xlink:to="loc_us-gaap_LiabilitiesCurrent_ff7183a7-b7d6-4620-812c-71036fb70e34" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityNoncurrent_4bfa21c3-9334-4d9f-9445-e3dc6597a418" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ContractWithCustomerLiabilityNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_88905f79-a746-4083-b2d5-f862175379de" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityNoncurrent_4bfa21c3-9334-4d9f-9445-e3dc6597a418" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_28e7b0fd-3303-4f59-a921-fa4a031599a9" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredIncomeTaxLiabilitiesNet"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_88905f79-a746-4083-b2d5-f862175379de" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_28e7b0fd-3303-4f59-a921-fa4a031599a9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_2230be0e-00a7-4756-ba9a-bbd9370ec9e8" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_88905f79-a746-4083-b2d5-f862175379de" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_2230be0e-00a7-4756-ba9a-bbd9370ec9e8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_f1178f0b-0dbd-48b0-95ec-ed2a0d961a48" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_88905f79-a746-4083-b2d5-f862175379de" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_f1178f0b-0dbd-48b0-95ec-ed2a0d961a48" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://docusign.com/role/CONDENSEDCONSOLIDATEDSTATEMENTSOFOPERATIONSANDCOMPREHENSIVEINCOMEUnaudited" xlink:type="simple" xlink:href="docu-20241031.xsd#CONDENSEDCONSOLIDATEDSTATEMENTSOFOPERATIONSANDCOMPREHENSIVEINCOMEUnaudited"/>
  <link:calculationLink xlink:role="http://docusign.com/role/CONDENSEDCONSOLIDATEDSTATEMENTSOFOPERATIONSANDCOMPREHENSIVEINCOMEUnaudited" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_f3093dc8-0456-4dfb-be28-96bb16700e8d" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_dd654912-2677-423e-b65d-64a60187a5da" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_f3093dc8-0456-4dfb-be28-96bb16700e8d" xlink:to="loc_us-gaap_NetIncomeLoss_dd654912-2677-423e-b65d-64a60187a5da" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_9e6c95e8-cf74-412e-be3e-d0e5895129bd" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_f3093dc8-0456-4dfb-be28-96bb16700e8d" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_9e6c95e8-cf74-412e-be3e-d0e5895129bd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_42ed02c5-cc5e-48b4-9ea7-09c72a373dce" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_GrossProfit"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_916ae45e-06b0-4fba-89ff-54e98d7de630" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_GrossProfit_42ed02c5-cc5e-48b4-9ea7-09c72a373dce" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_916ae45e-06b0-4fba-89ff-54e98d7de630" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_d3a1b59e-c11a-4ce8-9f57-21a546a976bb" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_GrossProfit_42ed02c5-cc5e-48b4-9ea7-09c72a373dce" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_d3a1b59e-c11a-4ce8-9f57-21a546a976bb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_c7d42253-61a8-4692-b315-b1156b1d8e3c" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_329475a3-37b6-470a-9067-f047591a8300" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_c7d42253-61a8-4692-b315-b1156b1d8e3c" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_329475a3-37b6-470a-9067-f047591a8300" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_1a445e49-e97e-4819-a9c9-d0ae11fa0ccc" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_c7d42253-61a8-4692-b315-b1156b1d8e3c" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_1a445e49-e97e-4819-a9c9-d0ae11fa0ccc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_687eddc3-3f1d-481e-be97-d2724df20621" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OperatingExpenses"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_9e688115-b2e1-4830-978c-e936eb59e02d" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_687eddc3-3f1d-481e-be97-d2724df20621" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_9e688115-b2e1-4830-978c-e936eb59e02d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_c72bf5a6-4522-490b-9680-b169feafa3c8" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_GeneralAndAdministrativeExpense"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_687eddc3-3f1d-481e-be97-d2724df20621" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_c72bf5a6-4522-490b-9680-b169feafa3c8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringCharges_8ab81e5f-46ba-4294-b3bb-314953f691a3" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_RestructuringCharges"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_687eddc3-3f1d-481e-be97-d2724df20621" xlink:to="loc_us-gaap_RestructuringCharges_8ab81e5f-46ba-4294-b3bb-314953f691a3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingAndMarketingExpense_5b6d1090-b463-44e8-a2fe-22cd5ef4f089" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_SellingAndMarketingExpense"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_687eddc3-3f1d-481e-be97-d2724df20621" xlink:to="loc_us-gaap_SellingAndMarketingExpense_5b6d1090-b463-44e8-a2fe-22cd5ef4f089" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_25766c1e-4eb3-41d1-994c-22b166bc68ea" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_64cd9347-e044-4c34-a33a-ceb2af27c327" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_GrossProfit"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_25766c1e-4eb3-41d1-994c-22b166bc68ea" xlink:to="loc_us-gaap_GrossProfit_64cd9347-e044-4c34-a33a-ceb2af27c327" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_4cea5729-76e1-43fd-86a5-04c92c4697f7" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OperatingExpenses"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_25766c1e-4eb3-41d1-994c-22b166bc68ea" xlink:to="loc_us-gaap_OperatingExpenses_4cea5729-76e1-43fd-86a5-04c92c4697f7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_59b4043e-3a12-4e22-8ed4-c17252a2f595" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_61fe42b9-e0bc-41b2-995e-8d7aea85632e" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_59b4043e-3a12-4e22-8ed4-c17252a2f595" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_61fe42b9-e0bc-41b2-995e-8d7aea85632e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_d9fedb6c-419e-408d-a7f0-0e533638c97f" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_59b4043e-3a12-4e22-8ed4-c17252a2f595" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_d9fedb6c-419e-408d-a7f0-0e533638c97f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_f890cd2a-eb7e-4273-afe1-8c1c5dd03b75" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_8e2f85a3-86af-48b8-8310-c247ca84f245" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_f890cd2a-eb7e-4273-afe1-8c1c5dd03b75" xlink:to="loc_us-gaap_OperatingIncomeLoss_8e2f85a3-86af-48b8-8310-c247ca84f245" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseNonoperating_7f81af67-8739-4d1e-b7b3-99e2d03173bf" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_InterestExpenseNonoperating"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_f890cd2a-eb7e-4273-afe1-8c1c5dd03b75" xlink:to="loc_us-gaap_InterestExpenseNonoperating_7f81af67-8739-4d1e-b7b3-99e2d03173bf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_76b4bc62-0ce1-4a75-9de6-0f1ee74c6458" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NonoperatingIncomeExpense"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_f890cd2a-eb7e-4273-afe1-8c1c5dd03b75" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_76b4bc62-0ce1-4a75-9de6-0f1ee74c6458" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://docusign.com/role/CONDENSEDCONSOLIDATEDSTATEMENTSOFCASHFLOWSUnaudited" xlink:type="simple" xlink:href="docu-20241031.xsd#CONDENSEDCONSOLIDATEDSTATEMENTSOFCASHFLOWSUnaudited"/>
  <link:calculationLink xlink:role="http://docusign.com/role/CONDENSEDCONSOLIDATEDSTATEMENTSOFCASHFLOWSUnaudited" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalizedContractCostAmortization_0e0b62ed-a1e2-4087-84d7-d604594d6011" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CapitalizedContractCostAmortization"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_us-gaap_CapitalizedContractCostAmortization_0e0b62ed-a1e2-4087-84d7-d604594d6011" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_c467e2ab-c96e-47c2-bc07-f866412e88f6" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_c467e2ab-c96e-47c2-bc07-f866412e88f6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_docu_IncreaseDecreaseInCapitalizedContractCost_51f4d664-0871-42f3-b6c3-4f969c3b169a" xlink:href="docu-20241031.xsd#docu_IncreaseDecreaseInCapitalizedContractCost"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_docu_IncreaseDecreaseInCapitalizedContractCost_51f4d664-0871-42f3-b6c3-4f969c3b169a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_b59b73d8-963e-441b-992f-717ed527a379" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_us-gaap_NetIncomeLoss_b59b73d8-963e-441b-992f-717ed527a379" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_53f8e9bb-7ebe-470b-bfd0-ff0886d46b44" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_53f8e9bb-7ebe-470b-bfd0-ff0886d46b44" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_829509a0-248d-451d-8bda-f41636aa7645" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AllocatedShareBasedCompensationExpense"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_829509a0-248d-451d-8bda-f41636aa7645" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxesAndTaxCredits_19fd8e33-9738-44b3-bc3f-4135e2083c50" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DeferredIncomeTaxesAndTaxCredits"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_us-gaap_DeferredIncomeTaxesAndTaxCredits_19fd8e33-9738-44b3-bc3f-4135e2083c50" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_4847498d-e932-41cd-8c7f-e08b6a25ccb1" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilities"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_4847498d-e932-41cd-8c7f-e08b6a25ccb1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_b6475dc2-e6b8-48cd-957f-b97e1ece0b72" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncreaseDecreaseInContractWithCustomerLiability"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_b6475dc2-e6b8-48cd-957f-b97e1ece0b72" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentAssets_556fdad4-6b4e-46fe-b016-3684339520a7" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncreaseDecreaseInOtherNoncurrentAssets"/>
    <link:calculationArc order="10" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentAssets_556fdad4-6b4e-46fe-b016-3684339520a7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_2941d091-d68b-4ec4-956f-b16030d8d944" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_2941d091-d68b-4ec4-956f-b16030d8d944" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingLeaseLiability_ff8aa4f0-4e55-4a27-ac4c-48f14cded9e6" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncreaseDecreaseInOperatingLeaseLiability"/>
    <link:calculationArc order="12" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingLeaseLiability_ff8aa4f0-4e55-4a27-ac4c-48f14cded9e6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_docu_NoncashOperatingLeaseCosts_4a20e87d-e7b0-40c3-8db7-ec95be4e3d27" xlink:href="docu-20241031.xsd#docu_NoncashOperatingLeaseCosts"/>
    <link:calculationArc order="13" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_docu_NoncashOperatingLeaseCosts_4a20e87d-e7b0-40c3-8db7-ec95be4e3d27" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_a5377fb0-91f9-42f2-8108-f9c8148a7ecf" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncreaseDecreaseInAccountsPayable"/>
    <link:calculationArc order="14" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_a5377fb0-91f9-42f2-8108-f9c8148a7ecf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities_25d531fc-aea5-45d8-bcd5-d2b00cbc3c12" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities"/>
    <link:calculationArc order="15" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities_25d531fc-aea5-45d8-bcd5-d2b00cbc3c12" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoncashIncomeExpense_65520b4c-5aeb-4ccb-8dc7-4ee42bebd671" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_OtherNoncashIncomeExpense"/>
    <link:calculationArc order="16" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_us-gaap_OtherNoncashIncomeExpense_65520b4c-5aeb-4ccb-8dc7-4ee42bebd671" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_93955c8f-a566-40ee-9127-af1b24abf01b" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets"/>
    <link:calculationArc order="17" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5f46ca27-a4d1-4568-8208-ada29065ee86" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_93955c8f-a566-40ee-9127-af1b24abf01b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_2ae9adc4-29cd-4284-9094-190ecde27f0a" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_5889fa29-6d15-4e3a-9626-87f1779967e9" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_2ae9adc4-29cd-4284-9094-190ecde27f0a" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_5889fa29-6d15-4e3a-9626-87f1779967e9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireMarketableSecurities_7b554f46-9de7-4765-924e-a4c15a54c66b" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PaymentsToAcquireMarketableSecurities"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_2ae9adc4-29cd-4284-9094-190ecde27f0a" xlink:to="loc_us-gaap_PaymentsToAcquireMarketableSecurities_7b554f46-9de7-4765-924e-a4c15a54c66b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_c69aa819-eea8-46b7-b5a4-57512d0404d2" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_2ae9adc4-29cd-4284-9094-190ecde27f0a" xlink:to="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_c69aa819-eea8-46b7-b5a4-57512d0404d2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_docu_PaymentsToAcquireStrategicInvestments_a4ba88e8-2ee1-45ab-a444-e4f5e9fffd1e" xlink:href="docu-20241031.xsd#docu_PaymentsToAcquireStrategicInvestments"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_2ae9adc4-29cd-4284-9094-190ecde27f0a" xlink:to="loc_docu_PaymentsToAcquireStrategicInvestments_a4ba88e8-2ee1-45ab-a444-e4f5e9fffd1e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_6dc76eec-a619-48d4-8710-c64afa401ccf" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_2ae9adc4-29cd-4284-9094-190ecde27f0a" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_6dc76eec-a619-48d4-8710-c64afa401ccf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_50d26c9b-aa13-4cbd-9c51-8193208332a4" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_66caa537-f8f0-467e-8a17-888e62ff5aa0" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_50d26c9b-aa13-4cbd-9c51-8193208332a4" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_66caa537-f8f0-467e-8a17-888e62ff5aa0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ac5d6948-3dc2-4239-b044-577a66c6c264" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_50d26c9b-aa13-4cbd-9c51-8193208332a4" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_ac5d6948-3dc2-4239-b044-577a66c6c264" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_2fa264ac-9fa7-4586-a26d-03ae712e4ecc" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_50d26c9b-aa13-4cbd-9c51-8193208332a4" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_2fa264ac-9fa7-4586-a26d-03ae712e4ecc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_d7f5e51a-3219-4991-8ead-1efb4f55ca88" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_50d26c9b-aa13-4cbd-9c51-8193208332a4" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_d7f5e51a-3219-4991-8ead-1efb4f55ca88" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_338457e5-0f00-4a77-9678-b3d61cb7c588" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_8db5f459-480a-41c8-bc57-dcf034b2d492" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ProceedsFromStockOptionsExercised"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_338457e5-0f00-4a77-9678-b3d61cb7c588" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_8db5f459-480a-41c8-bc57-dcf034b2d492" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_ec78cc07-f6f0-4661-a0d7-2e2e11a4304d" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_338457e5-0f00-4a77-9678-b3d61cb7c588" xlink:to="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_ec78cc07-f6f0-4661-a0d7-2e2e11a4304d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_9c84c8c4-349d-40fb-ba30-ef572a38fb70" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_338457e5-0f00-4a77-9678-b3d61cb7c588" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_9c84c8c4-349d-40fb-ba30-ef572a38fb70" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromDerivativeInstrumentFinancingActivities_7e2dbb1c-d980-42c3-a574-a32ea720786e" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ProceedsFromDerivativeInstrumentFinancingActivities"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_338457e5-0f00-4a77-9678-b3d61cb7c588" xlink:to="loc_us-gaap_ProceedsFromDerivativeInstrumentFinancingActivities_7e2dbb1c-d980-42c3-a574-a32ea720786e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromStockPlans_ff012dc0-cf21-41ca-a357-bba92b8ef2b0" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_ProceedsFromStockPlans"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_338457e5-0f00-4a77-9678-b3d61cb7c588" xlink:to="loc_us-gaap_ProceedsFromStockPlans_ff012dc0-cf21-41ca-a357-bba92b8ef2b0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfConvertibleDebt_eaeef584-0675-4e60-9819-b3007afea0b6" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_RepaymentsOfConvertibleDebt"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_338457e5-0f00-4a77-9678-b3d61cb7c588" xlink:to="loc_us-gaap_RepaymentsOfConvertibleDebt_eaeef584-0675-4e60-9819-b3007afea0b6" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://docusign.com/role/FairValueMeasurementsScheduleofAssetsandLiabilitiesMeasuredatFairValueonaRecurringBasisDetails" xlink:type="simple" xlink:href="docu-20241031.xsd#FairValueMeasurementsScheduleofAssetsandLiabilitiesMeasuredatFairValueonaRecurringBasisDetails"/>
  <link:calculationLink xlink:role="http://docusign.com/role/FairValueMeasurementsScheduleofAssetsandLiabilitiesMeasuredatFairValueonaRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLoss_ddb6ec20-be48-404b-a525-8698e1096e7e" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_d41fd896-ae6e-4bd1-a41d-3c5d37796b19" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLoss_ddb6ec20-be48-404b-a525-8698e1096e7e" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_d41fd896-ae6e-4bd1-a41d-3c5d37796b19" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_39044884-ea76-4fb6-964f-f3002153cd3a" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLoss_ddb6ec20-be48-404b-a525-8698e1096e7e" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_39044884-ea76-4fb6-964f-f3002153cd3a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest_b18f411e-ee54-489b-8b4e-f2203fcd29c6" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleAmortizedCostExcludingAccruedInterestAfterAllowanceForCreditLoss_ddb6ec20-be48-404b-a525-8698e1096e7e" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleExcludingAccruedInterest_b18f411e-ee54-489b-8b4e-f2203fcd29c6" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://docusign.com/role/FairValueMeasurementsScheduleofFairValueofAvailableforsaleMarketableSecuritiesbyRemainingContractualMaturitiesDetails" xlink:type="simple" xlink:href="docu-20241031.xsd#FairValueMeasurementsScheduleofFairValueofAvailableforsaleMarketableSecuritiesbyRemainingContractualMaturitiesDetails"/>
  <link:calculationLink xlink:role="http://docusign.com/role/FairValueMeasurementsScheduleofFairValueofAvailableforsaleMarketableSecuritiesbyRemainingContractualMaturitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_8340fe45-db76-4f57-a83d-183c55404030" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_3b7a6ac3-4763-486b-ac95-5f77e01db76a" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_8340fe45-db76-4f57-a83d-183c55404030" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_3b7a6ac3-4763-486b-ac95-5f77e01db76a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue_dd10e811-b14b-467b-b8cd-a7685e505423" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_8340fe45-db76-4f57-a83d-183c55404030" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue_dd10e811-b14b-467b-b8cd-a7685e505423" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://docusign.com/role/PropertyandEquipmentNetDetails" xlink:type="simple" xlink:href="docu-20241031.xsd#PropertyandEquipmentNetDetails"/>
  <link:calculationLink xlink:role="http://docusign.com/role/PropertyandEquipmentNetDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_024dd259-ba16-43a7-bbdc-c58351e5c437" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_eef282ad-fc89-4fa3-a16d-6bffeb79f70b" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_024dd259-ba16-43a7-bbdc-c58351e5c437" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_eef282ad-fc89-4fa3-a16d-6bffeb79f70b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_c74c1ad5-6ca7-4e06-80c2-eff392beeb67" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_024dd259-ba16-43a7-bbdc-c58351e5c437" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_c74c1ad5-6ca7-4e06-80c2-eff392beeb67" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://docusign.com/role/AcquisitionsScheduleofAssetsAcquiredAndLiabilitiesAssumedDetails" xlink:type="simple" xlink:href="docu-20241031.xsd#AcquisitionsScheduleofAssetsAcquiredAndLiabilitiesAssumedDetails"/>
  <link:calculationLink xlink:role="http://docusign.com/role/AcquisitionsScheduleofAssetsAcquiredAndLiabilitiesAssumedDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_07873d1c-97a0-4c8c-a81f-0e6f9358f906" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesDeferredRevenue_9c082820-e252-4c43-88da-8327ec6c11cd" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesDeferredRevenue"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_07873d1c-97a0-4c8c-a81f-0e6f9358f906" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesDeferredRevenue_9c082820-e252-4c43-88da-8327ec6c11cd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables_61cf97fe-8259-4cb8-85d5-e80bdba9fab3" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_07873d1c-97a0-4c8c-a81f-0e6f9358f906" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables_61cf97fe-8259-4cb8-85d5-e80bdba9fab3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill_fed0087f-00c6-4663-9512-f0b6446717f7" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_07873d1c-97a0-4c8c-a81f-0e6f9358f906" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill_fed0087f-00c6-4663-9512-f0b6446717f7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_c3d10900-0c3f-496e-ba11-dd1c9c1ff50b" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_07873d1c-97a0-4c8c-a81f-0e6f9358f906" xlink:to="loc_us-gaap_Goodwill_c3d10900-0c3f-496e-ba11-dd1c9c1ff50b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_ede36efb-f669-4202-ae70-a6ea00a41bd1" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_07873d1c-97a0-4c8c-a81f-0e6f9358f906" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_ede36efb-f669-4202-ae70-a6ea00a41bd1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_docu_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesDeferredTaxLiability_f0550f08-d474-4491-ad0e-1b4506aaf0ff" xlink:href="docu-20241031.xsd#docu_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesDeferredTaxLiability"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_07873d1c-97a0-4c8c-a81f-0e6f9358f906" xlink:to="loc_docu_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesDeferredTaxLiability_f0550f08-d474-4491-ad0e-1b4506aaf0ff" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_docu_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccruedExpensesAndOtherCurrentLiabilities_97b4cb21-f202-4991-bc3b-210fb806c3ca" xlink:href="docu-20241031.xsd#docu_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccruedExpensesAndOtherCurrentLiabilities"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_07873d1c-97a0-4c8c-a81f-0e6f9358f906" xlink:to="loc_docu_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccruedExpensesAndOtherCurrentLiabilities_97b4cb21-f202-4991-bc3b-210fb806c3ca" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://docusign.com/role/GoodwillandIntangibleAssetsNetScheduleofIntangibleAssetsDetails" xlink:type="simple" xlink:href="docu-20241031.xsd#GoodwillandIntangibleAssetsNetScheduleofIntangibleAssetsDetails"/>
  <link:calculationLink xlink:role="http://docusign.com/role/GoodwillandIntangibleAssetsNetScheduleofIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_docu_FiniteLivedIntangibleAssetsNetExcludingCumulativeTranslationAdjustments_137e16d7-85ea-4719-ad43-54054667d107" xlink:href="docu-20241031.xsd#docu_FiniteLivedIntangibleAssetsNetExcludingCumulativeTranslationAdjustments"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_8a3a5654-2254-46ca-8785-b7d73f11870d" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_docu_FiniteLivedIntangibleAssetsNetExcludingCumulativeTranslationAdjustments_137e16d7-85ea-4719-ad43-54054667d107" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_8a3a5654-2254-46ca-8785-b7d73f11870d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_284c63af-2210-4ae4-b651-c3d8682351e4" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_docu_FiniteLivedIntangibleAssetsNetExcludingCumulativeTranslationAdjustments_137e16d7-85ea-4719-ad43-54054667d107" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_284c63af-2210-4ae4-b651-c3d8682351e4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_3e3fb0b3-0411-4ab6-bfdd-c02200fe3c5b" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_docu_FiniteLivedIntangibleAssetsNetExcludingCumulativeTranslationAdjustments_847bff37-e14b-498d-b5c2-63b07f95facb" xlink:href="docu-20241031.xsd#docu_FiniteLivedIntangibleAssetsNetExcludingCumulativeTranslationAdjustments"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_3e3fb0b3-0411-4ab6-bfdd-c02200fe3c5b" xlink:to="loc_docu_FiniteLivedIntangibleAssetsNetExcludingCumulativeTranslationAdjustments_847bff37-e14b-498d-b5c2-63b07f95facb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_docu_FiniteLivedIntangibleAssetsCumulativeTranslationAdjustment_7ee342a5-1dbd-48fa-a205-de6f44d65e26" xlink:href="docu-20241031.xsd#docu_FiniteLivedIntangibleAssetsCumulativeTranslationAdjustment"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_3e3fb0b3-0411-4ab6-bfdd-c02200fe3c5b" xlink:to="loc_docu_FiniteLivedIntangibleAssetsCumulativeTranslationAdjustment_7ee342a5-1dbd-48fa-a205-de6f44d65e26" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://docusign.com/role/GoodwillandIntangibleAssetsNetScheduleofFutureAmortizationofFiniteLivedIntangiblesDetails" xlink:type="simple" xlink:href="docu-20241031.xsd#GoodwillandIntangibleAssetsNetScheduleofFutureAmortizationofFiniteLivedIntangiblesDetails"/>
  <link:calculationLink xlink:role="http://docusign.com/role/GoodwillandIntangibleAssetsNetScheduleofFutureAmortizationofFiniteLivedIntangiblesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_docu_FiniteLivedIntangibleAssetsNetExcludingCumulativeTranslationAdjustments_963c3d7b-6bf2-46c6-856f-601bddfe1780" xlink:href="docu-20241031.xsd#docu_FiniteLivedIntangibleAssetsNetExcludingCumulativeTranslationAdjustments"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_9e26dbb0-e04c-433f-8b80-fc67cff7b675" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_docu_FiniteLivedIntangibleAssetsNetExcludingCumulativeTranslationAdjustments_963c3d7b-6bf2-46c6-856f-601bddfe1780" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_9e26dbb0-e04c-433f-8b80-fc67cff7b675" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_8c3fd96b-3224-4458-9d4c-9b2dce9434cc" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_docu_FiniteLivedIntangibleAssetsNetExcludingCumulativeTranslationAdjustments_963c3d7b-6bf2-46c6-856f-601bddfe1780" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_8c3fd96b-3224-4458-9d4c-9b2dce9434cc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_a894230f-7f8a-4f32-b83d-4bd352ec3ee6" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_docu_FiniteLivedIntangibleAssetsNetExcludingCumulativeTranslationAdjustments_963c3d7b-6bf2-46c6-856f-601bddfe1780" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_a894230f-7f8a-4f32-b83d-4bd352ec3ee6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_af5627ca-25bd-4380-ae60-d26561c44cea" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_docu_FiniteLivedIntangibleAssetsNetExcludingCumulativeTranslationAdjustments_963c3d7b-6bf2-46c6-856f-601bddfe1780" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_af5627ca-25bd-4380-ae60-d26561c44cea" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_b20aa269-3c96-4a45-a686-8adbb1c2a995" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_docu_FiniteLivedIntangibleAssetsNetExcludingCumulativeTranslationAdjustments_963c3d7b-6bf2-46c6-856f-601bddfe1780" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_b20aa269-3c96-4a45-a686-8adbb1c2a995" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_docu_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour_32878fd0-7c2e-4edd-ba97-7f160874b84b" xlink:href="docu-20241031.xsd#docu_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_docu_FiniteLivedIntangibleAssetsNetExcludingCumulativeTranslationAdjustments_963c3d7b-6bf2-46c6-856f-601bddfe1780" xlink:to="loc_docu_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour_32878fd0-7c2e-4edd-ba97-7f160874b84b" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://docusign.com/role/DebtScheduleofInterestExpenseDetails" xlink:type="simple" xlink:href="docu-20241031.xsd#DebtScheduleofInterestExpenseDetails"/>
  <link:calculationLink xlink:role="http://docusign.com/role/DebtScheduleofInterestExpenseDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebt_c7318d92-ddc0-467f-bb70-b4fd73211bca" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_InterestExpenseDebt"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebtExcludingAmortization_868c765a-1522-4bac-bdbb-142a2cc39493" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_InterestExpenseDebtExcludingAmortization"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestExpenseDebt_c7318d92-ddc0-467f-bb70-b4fd73211bca" xlink:to="loc_us-gaap_InterestExpenseDebtExcludingAmortization_868c765a-1522-4bac-bdbb-142a2cc39493" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfFinancingCosts_9ecfbcaa-1753-4e09-8db2-4113411d92d3" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_AmortizationOfFinancingCosts"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestExpenseDebt_c7318d92-ddc0-467f-bb70-b4fd73211bca" xlink:to="loc_us-gaap_AmortizationOfFinancingCosts_9ecfbcaa-1753-4e09-8db2-4113411d92d3" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://docusign.com/role/CommitmentsandContingenciesScheduleofContractualObligationsDetails" xlink:type="simple" xlink:href="docu-20241031.xsd#CommitmentsandContingenciesScheduleofContractualObligationsDetails"/>
  <link:calculationLink xlink:role="http://docusign.com/role/CommitmentsandContingenciesScheduleofContractualObligationsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligation_c7ab8b1c-38d9-4556-b5e5-1cffe3ad4990" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PurchaseObligation"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationFutureMinimumPaymentsRemainderOfFiscalYear_11d13e3f-f4a0-478b-b201-35a3a68fd9a9" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PurchaseObligationFutureMinimumPaymentsRemainderOfFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PurchaseObligation_c7ab8b1c-38d9-4556-b5e5-1cffe3ad4990" xlink:to="loc_us-gaap_PurchaseObligationFutureMinimumPaymentsRemainderOfFiscalYear_11d13e3f-f4a0-478b-b201-35a3a68fd9a9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationDueInNextTwelveMonths_6197a712-f3bb-4d97-817e-c28768051789" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PurchaseObligationDueInNextTwelveMonths"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PurchaseObligation_c7ab8b1c-38d9-4556-b5e5-1cffe3ad4990" xlink:to="loc_us-gaap_PurchaseObligationDueInNextTwelveMonths_6197a712-f3bb-4d97-817e-c28768051789" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationDueInSecondYear_dd982ac6-cd5c-47f0-bede-22832cea47c2" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PurchaseObligationDueInSecondYear"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PurchaseObligation_c7ab8b1c-38d9-4556-b5e5-1cffe3ad4990" xlink:to="loc_us-gaap_PurchaseObligationDueInSecondYear_dd982ac6-cd5c-47f0-bede-22832cea47c2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationDueInThirdYear_508df388-a77f-451e-8c9f-46a5859d3773" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PurchaseObligationDueInThirdYear"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PurchaseObligation_c7ab8b1c-38d9-4556-b5e5-1cffe3ad4990" xlink:to="loc_us-gaap_PurchaseObligationDueInThirdYear_508df388-a77f-451e-8c9f-46a5859d3773" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationDueInFourthYear_112bd453-b3d2-43b5-a3c7-eb68e0d272b4" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_PurchaseObligationDueInFourthYear"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PurchaseObligation_c7ab8b1c-38d9-4556-b5e5-1cffe3ad4990" xlink:to="loc_us-gaap_PurchaseObligationDueInFourthYear_112bd453-b3d2-43b5-a3c7-eb68e0d272b4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_docu_PurchaseObligationToBePaidAfterYearFour_03ff8319-f52d-4a6f-85cc-9aea6837efbd" xlink:href="docu-20241031.xsd#docu_PurchaseObligationToBePaidAfterYearFour"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PurchaseObligation_c7ab8b1c-38d9-4556-b5e5-1cffe3ad4990" xlink:to="loc_docu_PurchaseObligationToBePaidAfterYearFour_03ff8319-f52d-4a6f-85cc-9aea6837efbd" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://docusign.com/role/NetIncomeperShareAttributabletoCommonStockholdersScheduleofCalculationofBasicandDilutedNetIncomePerShareAttributabletoCommonStockholdersDetails" xlink:type="simple" xlink:href="docu-20241031.xsd#NetIncomeperShareAttributabletoCommonStockholdersScheduleofCalculationofBasicandDilutedNetIncomePerShareAttributabletoCommonStockholdersDetails"/>
  <link:calculationLink xlink:role="http://docusign.com/role/NetIncomeperShareAttributabletoCommonStockholdersScheduleofCalculationofBasicandDilutedNetIncomePerShareAttributabletoCommonStockholdersDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_4bdf9761-922a-4a74-a1f9-f82e5747b856" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities_2b53a5d7-4ce5-475e-89c5-259623b3f1db" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_4bdf9761-922a-4a74-a1f9-f82e5747b856" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities_2b53a5d7-4ce5-475e-89c5-259623b3f1db" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_ace66f85-6741-4c69-96e4-9f9f8a145062" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_4bdf9761-922a-4a74-a1f9-f82e5747b856" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_ace66f85-6741-4c69-96e4-9f9f8a145062" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_396066b0-78e7-437c-9f0f-4e2d8a8631ac" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_383c95e3-2716-4a86-89cf-20be4693ec96" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_396066b0-78e7-437c-9f0f-4e2d8a8631ac" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_383c95e3-2716-4a86-89cf-20be4693ec96" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestOnConvertibleDebtNetOfTax_3eefbdb8-db96-48cd-82a0-a322a2bbf01f" xlink:href="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd#us-gaap_InterestOnConvertibleDebtNetOfTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_396066b0-78e7-437c-9f0f-4e2d8a8631ac" xlink:to="loc_us-gaap_InterestOnConvertibleDebtNetOfTax_3eefbdb8-db96-48cd-82a0-a322a2bbf01f" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
