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Summary of significant accounting policies - Narrative 2 (Details) - USD ($) $ in Thousands |  | 3 Months Ended | 6 Months Ended
--- | --- | --- | ---
Jan. 01, 2018 | Jun. 30, 2018 | Jun. 30, 2017 | Jun. 30, 2018 | Jun. 30, 2017
Revenue recognition |  |  |  |  |
Percentage of Medicare Part D insurance coverage gap mandate to be funded by manufacturers |  |  |  | 50.00% |
Recent Accounting Pronouncements |  |  |  |  |
Net income |  | $ 52,394 | $ (12,484) | $ 11,254 | $ (199,567)
ASU 2016-01 | Calithera |  |  |  |  |
Recent Accounting Pronouncements |  |  |  |  |
Net income | $ 2,800 |  |  |  |
ICLUSIG |  |  |  |  |
Revenue recognition |  |  |  |  |
Amortization period |  |  |  | 12 years 6 months |

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- Definition Represents the percentage of Medicare Part D insurance coverage gap mandate to be funded by manufacturers for prescription drugs sold to eligible patients. + References No definition available. + Details
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