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Revenues (Details) - USD ($) $ in Thousands | 3 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2018 | Sep. 30, 2018 | Jun. 30, 2018 | Mar. 31, 2018 | Dec. 31, 2017 | Sep. 30, 2017 | Jun. 30, 2017 | Mar. 31, 2017 | Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016
Revenues |  |  |  |  |  |  |  |  |  |  |
Total revenues | $ 528,402 | $ 449,683 | $ 521,516 | $ 382,282 | $ 444,156 | $ 381,534 | $ 326,444 | $ 384,082 | $ 1,881,883 |  |
Before topic 606 |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  |  |  |  |  |  |  |
Total revenues |  |  |  |  |  |  |  |  |  | $ 1,536,216 | $ 1,105,719
Product revenues, net |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  |  |  |  |  |  |  |
Total revenues | 399,200 | 367,700 | 365,500 | 334,500 | 321,800 | 322,000 | 291,700 | 264,800 | 1,466,900 | 1,200,312 | 882,404
JAKAFI |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  |  |  |  |  |  |  |
Total revenues |  |  |  |  |  |  |  |  | 1,386,964 | 1,133,392 | 852,816
ICLUSIG |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  |  |  |  |  |  |  |
Total revenues |  |  |  |  |  |  |  |  | 79,936 | 66,920 | 29,588
Product royalty revenues |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  |  |  |  |  |  |  |
Total revenues |  |  |  |  |  |  |  |  | 234,780 | 160,791 | 110,711
JAKAVI Royalty Revenues |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  |  |  |  |  |  |  |
Total revenues |  |  |  |  |  |  |  |  | 194,694 | 151,684 | 110,711
OLUMIANT Royalty Revenues |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  |  |  |  |  |  |  |
Total revenues |  |  |  |  |  |  |  |  | 40,086 | 9,107 |
Milestone and contract revenues |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  |  |  |  |  |  |  |
Total revenues | $ 60,000 | $ 20,000 | $ 100,000 | $ 0 | $ 70,000 | $ 15,000 | $ 0 | $ 90,000 | 180,000 | 175,000 | 112,512
Other revenues |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  |  |  |  |  |  |  |
Total revenues |  |  |  |  |  |  |  |  | $ 203 | $ 113 | $ 92

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