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Income Taxes - Tax Credit Carryforwards (Details) $ in Thousands	Dec. 31, 2018 USD ($)
Orphan drug tax credit carryforwards
Tax Credit Carryforward
Tax credit carryforward	$ 210,242
Federal | Research and development
Tax Credit Carryforward
Tax credit carryforward	197,400
State | Research and development
Tax Credit Carryforward
Tax credit carryforward	$ 25,247

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- Definition

The amount of the tax credit carryforward, before tax effects, available to reduce future taxable income under enacted tax laws.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 740
-SubTopic 10
-Section 50
-Paragraph 3
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=84230637&loc=d3e32559-109319

+ Details

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+ References

No definition available.

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