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Business Combination - Narratives (Details)
$ in Millions
12 Months Ended
Jun. 01, 2016
USD ($)
Dec. 31, 2017
USD ($)
Dec. 31, 2016
USD ($)
Maximum      
Business combinations      
Potential future oncology development and regulatory approval milestone payments $ 135.0    
ARIAD      
Business combinations      
Upfront Payment 147.5    
Fair value of consideration transferred      
Fair value of consideration transferred 440.5    
Cash 147.5    
Contingent consideration $ 293.0    
ARIAD | Contingent Consideration      
Fair value of consideration transferred      
Probability of technical success (“PTS”) (as a percent) 25.00%    
Projected cash flows period 18 years    
ARIAD | Contingent Consideration | Discount rate      
Fair value of consideration transferred      
Discount rate (as a percent) 10    
ARIAD | Minimum      
Business combinations      
Royalties paid (as a percentage) 32.00%    
ARIAD | Maximum      
Business combinations      
Royalties paid (as a percentage) 50.00%    
Development costs   $ 7.0 $ 7.0