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License agreements - Innovent (Details) - Innovent $ in Millions | 1 Months Ended
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Jan. 31, 2019 USD ($) | Dec. 31, 2018 USD ($) item
License agreements |  |
Upfront and immediate milestone payment to be received under license agreement | $ 40.0 |
Product candidates | item |  | 3
Regulatory Milestones | Maximum |  |
License agreements |  |
Upfront and immediate milestone payment to be received under license agreement |  | $ 20.0
Development and Regulatory Milestones | Maximum |  |
License agreements |  |
Upfront and immediate milestone payment to be received under license agreement |  | 129.0
Commercialization Milestones | Maximum |  |
License agreements |  |
Upfront and immediate milestone payment to be received under license agreement |  | $ 202.5

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