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Concentration of credit risk (Details) | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2019 | Mar. 31, 2018 | Dec. 31, 2018
Milestone Revenues | Customer Concentration Risk | Collaboration Partner C |  |  |
Concentration of risk |  |  |
Percentage of concentration risk | 100.00% |  |
Net Product Revenues | Customer Concentration Risk | Customer A |  |  |
Concentration of risk |  |  |
Percentage of concentration risk | 18.00% | 22.00% |
Net Product Revenues | Customer Concentration Risk | Customer B |  |  |
Concentration of risk |  |  |
Percentage of concentration risk | 15.00% | 13.00% |
Net Product Revenues | Customer Concentration Risk | Customer C |  |  |
Concentration of risk |  |  |
Percentage of concentration risk | 16.00% | 14.00% |
Net Product Revenues | Customer Concentration Risk | Customer D |  |  |
Concentration of risk |  |  |
Percentage of concentration risk | 12.00% | 11.00% |
Accounts Receivable | Credit Concentration Risk | Collaboration Partner A, B and C |  |  |
Concentration of risk |  |  |
Percentage of concentration risk | 26.00% |  | 42.00%
Accounts Receivable | Credit Concentration Risk | Customer A, B, C and D |  |  |
Concentration of risk |  |  |
Percentage of concentration risk | 37.00% |  | 30.00%

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