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Summary of significant accounting policies - Narrative 1 (Details)
 3 Months Ended
Mar. 31, 2019
item
issuer
instrument
Concentrations of Credit Risk  
Number of issuer to which company limits the amount of credit exposure other than US Government guaranteed securities | issuer 1
Number of financial investment to which company limits the amount of credit exposure other than US Government guaranteed securities | instrument 1
Variable Interest Entities  
Number of entities in which variable interest held | item 0
JAKAFI  
Inventory  
Shelf life for finished goods inventory, maximum 36 months
ICLUSIG  
Inventory  
Shelf life for finished goods inventory, maximum 24 months