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License agreements - Innovent (Details) - Innovent $ in Millions	1 Months Ended
	Jan. 31, 2019 USD ($)	Dec. 31, 2018 USD ($) item
License agreements
Upfront and immediate milestone payment to be received under license agreement	$ 40.0
Product candidates | item		3
Regulatory Milestones | Maximum
License agreements
Upfront and immediate milestone payment to be received under license agreement		$ 20.0
Development and Regulatory Milestones | Maximum
License agreements
Upfront and immediate milestone payment to be received under license agreement		129.0
Commercialization Milestones | Maximum
License agreements
Upfront and immediate milestone payment to be received under license agreement		$ 202.5

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- Definition

Represents the upfront and immediate milestone payment received under the license agreement.

+ References

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- Definition

Represents the number of clinical-stage product candidates .

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- Definition

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