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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Cash flows from operating activities:    
Net income $ 335,901 $ 40,430
Adjustments to reconcile net income to net cash provided by operating activities:    
Depreciation and amortization 41,188 40,743
Stock-based compensation 124,566 110,830
Other, net 356 258
Unrealized (gain) loss on long term investments (18,703) 21,911
Change in fair value of acquisition-related contingent consideration 16,560 18,708
Changes in operating assets and liabilities:    
Accounts receivable 31,482 18,563
Prepaid expenses and other assets 9,999 (21,330)
Inventory (2,913) 3,030
Accounts payable (8,451) 27,807
Accrued and other liabilities 49,053 (8,561)
Net cash provided by operating activities 579,038 252,389
Cash flows from investing activities:    
Purchase of long term investments   (8,936)
Capital expenditures (48,749) (48,202)
Purchases of marketable securities (222,157) (104,228)
Sale and maturities of marketable securities 213,480 111,040
Net cash used in investing activities (57,426) (50,326)
Cash flows from financing activities:    
Proceeds from issuance of common stock under stock plans 33,783 20,480
Payment of finance lease liabilities (626)  
Payment of contingent consideration (16,766) (9,886)
Net cash provided by financing activities 16,391 10,594
Effect of exchange rates on cash, cash equivalents, restricted cash and investments 29 97
Net increase in cash, cash equivalents, restricted cash and investments 538,032 212,754
Cash, cash equivalents, restricted cash and investments at beginning of period 1,164,986 900,434
Cash, cash equivalents, restricted cash and investments at end of period 1,703,018 1,113,188
Supplemental Schedule of Cash Flow Information    
Interest paid 119 134
Income taxes paid 12,398 2,932
Leased assets obtained in exchange for new operating lease liabilities 6,686  
Leased assets obtained in exchange for new finance lease liabilities $ 29,740  
Convertible Senior Notes 0.375 Percent Due 2018    
Supplemental Schedule of Cash Flow Information    
Reclassification to common stock and additional paid in capital in connection with conversions of 0.375% convertible senior notes due 2018   $ 31