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License agreements - Innovent (Details) - Innovent $ in Millions | 1 Months Ended | 12 Months Ended
--- | --- | ---
Jun. 30, 2019 USD ($) | Jan. 31, 2019 USD ($) | Dec. 31, 2018 USD ($) item | Dec. 31, 2019 USD ($)
License agreements |  |  |  |
Upfront and immediate milestone payment to be received under license agreement |  | $ 40.0 |  |
Research and development expenses reimbursed |  |  |  | $ 6.2
Reimbursable costs included in accounts receivable |  |  |  | $ 3.0
Product candidates | item |  |  | 3 |
Regulatory Milestones |  |  |  |
License agreements |  |  |  |
Milestone payment made under license agreement | $ 20.0 |  |  |
Regulatory Milestones | Maximum |  |  |  |
License agreements |  |  |  |
Upfront and immediate milestone payment to be received under license agreement |  |  | $ 20.0 |
Development and Regulatory Milestones | Maximum |  |  |  |
License agreements |  |  |  |
Upfront and immediate milestone payment to be received under license agreement |  |  | 129.0 |
Commercialization Milestones | Maximum |  |  |  |
License agreements |  |  |  |
Upfront and immediate milestone payment to be received under license agreement |  |  | $ 202.5 |

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