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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (Parenthetical) - shares | 12 Months Ended
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Dec. 31, 2019 | Dec. 31, 2018 | Dec. 31, 2017
Issuance of shares of Common Stock upon exercise of stock options and restricted stock units | 2,657,892 | 1,624,376 | 3,012,937
Issuance of shares of Common Stock under the ESPP | 239,590 | 233,712 | 157,277
Issuance of shares of Common Stock for services rendered | 5,688 | 4,905 | 2,532
Issuance of shares of Common Stock |  |  | 4,945,000
Convertible Senior Notes 1.25 Percent Due 2020 |  |  |
Issuance of shares of Common Stock upon conversion of convertible senior notes |  |  | 7,095,350
Convertible Senior Notes 0.375 Percent Due 2018 |  |  |
Issuance of shares of Common Stock upon conversion of convertible senior notes |  | 148,761 | 7,201,058

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- Definition Number of shares issued during the period as a result of an employee stock purchase plan. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=109259400&loc=d3e21463-112644 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.3-04) -URI http://asc.fasb.org/extlink&oid=27012166&loc=d3e187085-122770 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(28)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(29)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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