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Organization and Summary of Significant Accounting Policies (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2019 USD ($) item	Jun. 30, 2019 USD ($)	Jan. 01, 2019 USD ($)	Dec. 31, 2018 USD ($)	Jan. 01, 2018 USD ($)
Organization and Business
Number of operating segments | item	1
Concentrations of Credit Risk
Number of issuer to which company limits the amount of credit exposure other than US Government guaranteed securities | item	1
Number of financial investment to which company limits the amount of credit exposure other than US Government guaranteed securities | item	1
Variable Interest Entities Abstract
Number of entities in which variable interest held | item	0
Revenue Recognition
Percentage of Medicare Part D insurance coverage gap mandate to be funded by manufacturers	70.00%
Recent Accounting Pronouncements
Lease liabilities	$ 53,779
Retained earnings	(1,430,758)			$ (1,877,759)
Capital lease obligations				18,696
Financing lease liabilities	$ 32,582
Office Building in Morges, Switzerland
Recent Accounting Pronouncements
Financing lease liabilities		$ 31,100
Office Building in Morges, Switzerland | Building and leasehold improvements
Recent Accounting Pronouncements
Capital lease obligations				18,700
Capital lease asset				$ 18,700
Calithera | ASU 2016-01
Accumulated Other Comprehensive Income (Loss)
Decrease in accumulated deficit					$ 2,800
JAKAFI
Inventory
Shelf life for finished goods inventory, maximum	36 months
ICLUSIG
Revenue Recognition
Amortization period	12 years 6 months
Restatement Adjustment | ASU 2016-02
Recent Accounting Pronouncements
Lease right-of-use assets			$ 23,600
Lease liabilities			23,700
Retained earnings			$ 100

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