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Interim Consolidated Financial Information (Unaudited) - Narrative (Details) - USD ($) $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2019	Sep. 30, 2019	Jun. 30, 2019	Mar. 31, 2019	Dec. 31, 2018	Sep. 30, 2018	Jun. 30, 2018	Mar. 31, 2018	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Interim Consolidated Financial Information (Unaudited)
Revenues	$ 579,389	$ 551,581	$ 529,932	$ 497,857	$ 528,402	$ 449,683	$ 521,516	$ 382,282	$ 2,158,759	$ 1,881,883	$ 1,536,216
Product revenues, net
Interim Consolidated Financial Information (Unaudited)
Revenues	490,800	454,000	433,900	396,200	399,200	367,700	365,500	334,500	1,774,922	1,466,900	1,200,312
Product royalty revenues
Interim Consolidated Financial Information (Unaudited)
Revenues									306,337	234,780	160,791
Product royalty revenues | Non-U.S.
Interim Consolidated Financial Information (Unaudited)
Revenues	88,600	80,100	76,000	61,600	69,200	61,900	56,000	47,700
Milestone and contract revenues
Interim Consolidated Financial Information (Unaudited)
Revenues	$ 0	$ 17,500	$ 20,000	$ 40,000	$ 60,000	$ 20,000	$ 100,000	$ 0	$ 77,500	$ 180,000	$ 175,000

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
-SubTopic 10
-Section 50
-Paragraph 4
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=118956577&loc=SL49130543-203045

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
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-Section 50
-Paragraph 5
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