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License agreements - MorphoSys (Details) - USD ($) $ / shares in Units, $ in Thousands |  | 1 Months Ended | 3 Months Ended |
--- | --- | --- | --- | ---
Mar. 03, 2020 | Mar. 31, 2020 | Jan. 31, 2020 | Mar. 31, 2020 | Mar. 31, 2019 | Dec. 31, 2019 | [1]
Unrealized gain (loss) on long term investments |  |  |  | $ (48,132) | $ 20,989 |
Long term investments |  | $ 180,993 |  | 180,993 |  | $ 133,657
Research and development expense |  |  |  | 1,085,287 | $ 270,545 |
Collaboration loss sharing |  |  |  | 2,130 |  |
ADSs |  |  |  |  |  |
Equity Method Investment, Ownership Percentage |  |  | 25.00% |  |  |
Equity Method Investment, Aggregate Cost |  |  | $ 150,000 |  |  |
Per share price | $ 27.65 |  | $ 41.33 |  |  |
Lock-up period |  |  | 18 months |  |  |
Discount for lack of marketability | $ 4,900 |  |  |  |  |
Fair value of shares | 95,500 | 85,600 |  | $ 85,600 |  |
Long term investments | 95,500 |  |  |  |  |
Research and development expense | $ 54,500 |  |  |  |  |
MorphoSys AG |  |  |  |  |  |
Upfront payment under license agreement |  | $ 750,000 |  |  |  |
Equity Method Investment, Ownership Percentage |  | 3.00% |  | 3.00% |  |
Unrealized gain (loss) on long term investments |  |  |  | $ (9,900) |  |
Research and development expense |  |  |  | $ 11,600 |  |
Profit (loss) sharing ratio |  |  |  | 50.00% |  |
Collaboration loss sharing |  |  |  | $ 2,100 |  |
MorphoSys AG | Accrued and other liabilities |  |  |  |  |  |
Accrued and other liabilities |  | $ 13,100 |  | $ 13,100 |  |
MorphoSys AG | Development and Regulatory Milestones | Maximum |  |  |  |  |  |
Additional milestone payments under the license agreement |  |  | $ 740,000 |  |  |
MorphoSys AG | Commercialization Milestones | Maximum |  |  |  |  |  |
Additional milestone payments under the license agreement |  |  | $ 315,000 |  |  |
MorphoSys AG | MorphoSys AG |  |  |  |  |  |
Funding of future development costs (as a percent) |  |  | 45.00% |  |  |
MorphoSys AG | Incyte |  |  |  |  |  |
Funding of future development costs (as a percent) |  |  | 55.00% | 55.00% |  |
[1] | The condensed consolidated balance sheet at December 31, 2019 has been derived from the audited consolidated financial statements at that date.

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