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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands, $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2020 | Mar. 31, 2019
Revenues: |  |
Total revenues | $ 568,507 | $ 497,857
Costs and expenses: |  |
Cost of product revenues (including definite-lived intangible amortization) | 27,319 | 22,588
Research and development | 1,085,287 | 270,545
Selling, general and administrative | 111,148 | 123,983
Change in fair value of acquisition-related contingent consideration | 6,627 | 6,671
Collaboration loss sharing | 2,130 |
Total costs and expenses | 1,232,511 | 423,787
Income (loss) from operations | (664,004) | 74,070
Other income (expense), net | 8,662 | 9,373
Interest expense | (602) | (335)
Unrealized gain (loss) on long term investments | (48,132) | 20,989
Income (loss) before provision for income taxes | (704,076) | 104,097
Provision for income taxes | 16,566 | 1,785
Net (loss) income | $ (720,642) | $ 102,312
Net income (loss) per share: |  |
Basic | $ (3.33) | $ 0.48
Diluted | $ (3.33) | $ 0.47
Shares used in computing net income (loss) per share: |  |
Basic | 216,721 | 214,065
Diluted | 216,721 | 217,061
Product revenues, net |  |
Revenues: |  |
Total revenues | $ 486,727 | $ 396,249
Product royalty revenues |  |
Revenues: |  |
Total revenues | $ 81,780 | 61,608
Milestone and contract revenues |  |
Revenues: |  |
Total revenues |  | $ 40,000

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