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License agreements - Innovent (Details) - Innovent - USD ($) $ in Millions | 1 Months Ended | 3 Months Ended | 6 Months Ended |
--- | --- | --- | --- | ---
Apr. 30, 2020 | Jun. 30, 2019 | Jan. 31, 2019 | Dec. 31, 2018 | Jun. 30, 2020 | Jun. 30, 2019 | Jun. 30, 2020 | Jun. 30, 2019 | Dec. 31, 2019
License agreements |  |  |  |  |  |  |  |  |
Upfront and immediate milestone payment to be received under license agreement |  |  | $ 40.0 |  |  |  |  |  |
Research and development expenses reimbursed |  |  |  |  | $ 2.6 | $ 0.5 | $ 2.6 | $ 0.5 |
Reimbursable costs included in accounts receivable |  |  |  |  | $ 2.2 |  | $ 2.2 |  | $ 3.0
Regulatory Milestones |  |  |  |  |  |  |  |  |
License agreements |  |  |  |  |  |  |  |  |
Amount recognized and received for the achievement of a predefined milestone |  | $ 20.0 |  |  |  |  |  |  |
Regulatory Milestones | PEMAZYRE |  |  |  |  |  |  |  |  |
License agreements |  |  |  |  |  |  |  |  |
Amount recognized and received for the achievement of a predefined milestone | $ 5.0 |  |  |  |  |  |  |  |
Development and Regulatory Milestones | Maximum |  |  |  |  |  |  |  |  |
License agreements |  |  |  |  |  |  |  |  |
Upfront and immediate milestone payment to be received under license agreement |  |  |  | $ 129.0 |  |  |  |  |
Sales and Commercial Milestones | Maximum |  |  |  |  |  |  |  |  |
License agreements |  |  |  |  |  |  |  |  |
Upfront and immediate milestone payment to be received under license agreement |  |  |  | $ 202.5 |  |  |  |  |

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