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Fair value of financial instruments - Fair value on a recurring basis (Details) $ in Thousands |  | 9 Months Ended | 12 Months Ended
--- | --- | --- | ---
Jun. 01, 2016 | Sep. 30, 2020 USD ($) | Dec. 31, 2019 USD ($)
Fair value of financial instruments |  |  |
Long term investments (Note 9) |  | $ 222,810 | $ 133,657
ARIAD | Contingent Consideration |  |  |
Roll forward of Level 3 liabilities |  |  |
Projected cash flows period | 18 years |  |
ARIAD | Discount rate | Contingent Consideration |  |  |
Roll forward of Level 3 liabilities |  |  |
Valuation input (as a percent) | 10 |  |
ARIAD | Average Cost of Capital | Contingent Consideration |  |  |
Roll forward of Level 3 liabilities |  |  |
Valuation input (as a percent) |  | 10 |
ARIAD | Accrued and other current liabilities |  |  |
Roll forward of Level 3 liabilities |  |  |
Contingent consideration earned during the period but not yet paid |  | $ (9,100) | (23,000)
Level 3 | Fair Value |  |  |
Roll forward of Level 3 liabilities |  |  |
Balance at the beginning of the period |  | 277,000 |
Contingent consideration earned during the period but not yet paid |  | (9,109) |
Payments made during the period |  | (15,681) |
Change in fair value of contingent consideration |  | 19,790 |
Balance at the end of the period |  | 272,000 | 277,000
Recurring | Fair Value |  |  |
Fair value of financial instruments |  |  |
Cash and cash equivalents |  | 1,497,775 | 1,832,684
Debt securities (government) |  | 237,025 | 284,870
Long term investments (Note 9) |  | 222,810 | 133,657
Total assets |  | 1,957,610 | 2,251,211
Acquisition-related contingent consideration |  | 272,000 | 277,000
Total liabilities |  | 272,000 | 277,000
Recurring | Level 1 |  |  |
Fair value of financial instruments |  |  |
Cash and cash equivalents |  | 1,497,775 | 1,832,684
Long term investments (Note 9) |  | 222,810 | 133,657
Total assets |  | 1,720,585 | 1,966,341
Recurring | Level 2 |  |  |
Fair value of financial instruments |  |  |
Debt securities (government) |  | 237,025 | 284,870
Total assets |  | 237,025 | 284,870
Recurring | Level 3 |  |  |
Fair value of financial instruments |  |  |
Acquisition-related contingent consideration |  | 272,000 | 277,000
Total liabilities |  | $ 272,000 | $ 277,000

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