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Revenues (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Revenues        
Total revenues $ 620,643 $ 551,581 $ 1,877,193 $ 1,579,370
Product revenues, net        
Revenues        
Total revenues 522,252 453,998 1,509,269 1,284,144
JAKAFI        
Revenues        
Total revenues 487,783 433,387 1,420,968 1,218,504
ICLUSIG        
Revenues        
Total revenues 26,380 20,611 76,426 65,640
PEMAZYRE        
Revenues        
Total revenues 8,089   11,875  
Product royalty revenues        
Revenues        
Total revenues 98,391 80,083 272,924 217,726
JAKAVI Royalty Revenues        
Revenues        
Total revenues 68,306 58,440 190,856 160,906
OLUMIANT Royalty Revenues        
Revenues        
Total revenues 28,647 21,643 79,924 56,820
TABRECTA Royalty Revenues        
Revenues        
Total revenues $ 1,438   2,144  
Milestone and contract revenues        
Revenues        
Total revenues   $ 17,500 $ 95,000 $ 77,500