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Property and equipment, net - Property and equipment, net (Details) - USD ($) $ in Thousands	Sep. 30, 2020	Dec. 31, 2019
Property and equipment, net
Property and Equipment, gross	$ 635,483	$ 499,437
Less accumulated depreciation and amortization	(137,148)	(121,870)
Property and Equipment, net	498,335	377,567
Office equipment
Property and equipment, net
Property and Equipment, gross	14,530	15,303
Laboratory equipment
Property and equipment, net
Property and Equipment, gross	74,960	70,510
Computer equipment
Property and equipment, net
Property and Equipment, gross	61,964	59,069
Land
Property and equipment, net
Property and Equipment, gross	10,447	10,203
Building and leasehold improvements
Property and equipment, net
Property and Equipment, gross	206,600	208,293
Operating lease right-of-use assets
Property and equipment, net
Property and Equipment, gross	23,862	19,672
Construction in Progress
Property and equipment, net
Property and Equipment, gross	$ 243,120	$ 116,387

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- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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