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License agreements - MorphoSys (Details)
$ / shares in Units, $ in Thousands, € in Millions
1 Months Ended 3 Months Ended 9 Months Ended
Mar. 03, 2020
USD ($)
$ / shares
Mar. 31, 2020
EUR (€)
Jan. 31, 2020
USD ($)
$ / shares
Sep. 30, 2020
USD ($)
Sep. 30, 2019
USD ($)
Sep. 30, 2020
USD ($)
Sep. 30, 2019
USD ($)
Dec. 31, 2019
USD ($)
Unrealized gain (loss) on long term investments       $ (13,207) $ 2,339 $ 10,935 $ 18,703  
Long term investments       222,810   222,810   $ 133,657
Research and development expense       438,109 $ 281,336 1,809,997 $ 841,244  
Collaboration loss sharing       14,989   30,372    
ADSs                
Equity Method Investment, Ownership Percentage     25.00%          
Equity Method Investment, Aggregate Cost     $ 150,000          
Per share price | $ / shares $ 27.65   $ 41.33          
Lock-up period     18 months          
Discount for lack of marketability $ 4,900              
Fair value of shares 95,500              
Long term investments 95,500     $ 113,900   $ 113,900    
Research and development expense $ 54,500              
MorphoSys AG                
Upfront payment under license agreement | €   € 750.0            
Equity Method Investment, Ownership Percentage       3.00%   3.00%    
Unrealized gain (loss) on long term investments       $ 900   $ 18,500    
Research and development expense       23,800   $ 51,100    
Associated future global development costs from the initiation of a Phase IIb trial, if elected to co-develop (as a percentage)           55.00%    
Accrued and other liabilities       46,800   $ 46,800    
Profit (loss) sharing ratio           50.00%    
Collaboration loss sharing       $ 15,000   $ 30,400    
MorphoSys AG | Development and Regulatory Milestones | Maximum                
Additional milestone payments under the license agreement     $ 740,000          
MorphoSys AG | Sales and Commercial Milestones | Maximum                
Additional milestone payments under the license agreement     $ 315,000          
MorphoSys AG | MorphoSys AG                
Funding of future development costs (as a percent)           45.00%    
MorphoSys AG | Incyte                
Funding of future development costs (as a percent)           55.00%