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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Cash flows from operating activities:    
Net income (loss) $ (445,547) $ 335,901
Adjustments to reconcile net income to net cash provided by operating activities:    
Depreciation and amortization 38,641 41,188
Stock-based compensation 132,616 124,566
Other, net 8,698 356
Unrealized gain on long term investments (10,935) (18,703)
Change in fair value of acquisition-related contingent consideration 19,790 16,560
Changes in operating assets and liabilities:    
Accounts receivable (55,656) 31,482
Prepaid expenses and other assets (11,384) 9,999
Inventory (9,204) (2,913)
Accounts payable 38,865 (8,451)
Accrued and other liabilities 62,196 49,053
Net cash (used in) provided by operating activities (231,920) 579,038
Cash flows from investing activities:    
Purchase of long term investments (95,468)  
Sale of long term investment 17,250  
Capital expenditures (135,946) (48,749)
Purchases of marketable securities (418,698) (222,157)
Sale and maturities of marketable securities 466,591 213,480
Net cash used in investing activities (166,271) (57,426)
Cash flows from financing activities:    
Proceeds from issuance of common stock under stock plans 91,596 33,783
Payment of finance lease liabilities (619) (626)
Payment of contingent consideration (31,140) (16,766)
Net cash provided by financing activities 59,837 16,391
Effect of exchange rates on cash, cash equivalents, restricted cash and investments 5,085 29
Net (decrease) increase in cash, cash equivalents, restricted cash and investments (333,269) 538,032
Cash, cash equivalents, restricted cash and investments at beginning of period 1,833,707 1,164,986
Cash, cash equivalents, restricted cash and investments at end of period 1,500,438 1,703,018
Supplemental Schedule of Cash Flow Information    
Interest paid 119 119
Income taxes paid 56,757 12,398
Reclassification to common stock and additional paid in capital in connection with conversions of 1.25% convertible senior notes due 2020 6,992  
Unpaid purchases of property and equipment 12,836  
Leased assets obtained in exchange for new operating lease liabilities 13,020 6,686
Leased assets obtained in exchange for new finance lease liabilities $ 2,160 $ 29,740