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License Agreements - MorphoSys (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
Mar. 03, 2020
Jan. 31, 2020
Mar. 31, 2019
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Long term investments       $ 222,301 $ 133,657  
Research and development expense       2,215,942 1,154,111 $ 1,197,957
Unrealized gain (loss) on long term investments       10,426 $ 34,458 $ (44,093)
Collaboration loss sharing       42,801    
ADSs            
Equity Method Investment, Ownership Percentage   0.25%        
Equity Method Investment, Aggregate Cost $ 150,000 $ 150,000        
Per share price $ 27.65 $ 41.33        
Lock-up period   18 months        
Discount for lack of marketability $ 4,900          
Fair value of shares 95,500          
Long term investments 95,500     $ 102,900    
Research and development expense $ 54,500          
MorphoSys AG            
Upfront payment under license agreement     $ 750,000      
Equity Method Investment, Ownership Percentage       0.03%    
Research and development expense       $ 88,200    
Unrealized gain (loss) on long term investments       $ 7,400    
Profit (loss) sharing ratio       50.00%    
Collaboration loss sharing       $ 42,800    
Associated future global development costs from the initiation of a Phase IIb trial, if elected to co-develop (as a percentage)       0.55%    
Accrued and other liabilities       $ 54,200    
MorphoSys AG | Development and Regulatory Milestones | Maximum            
Additional milestone payments under the license agreement   $ 740,000        
MorphoSys AG | Sales and Commercial Milestones | Maximum            
Additional milestone payments under the license agreement   $ 315,000        
MorphoSys AG | MorphoSys AG            
Funding of future development costs (as a percent)       0.45%    
MorphoSys AG | Incyte            
Funding of future development costs (as a percent)       0.55%