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License Agreements - MacroGenics (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 40 Months Ended
Dec. 31, 2017
Mar. 31, 2021
Mar. 31, 2020
Mar. 31, 2021
Dec. 31, 2020
License agreements          
Research and development   $ 306,896 $ 1,085,287    
MacroGenics          
License agreements          
Upfront payment under license agreement $ 150,000        
Research and development   13,600 $ 16,400    
MacroGenics | Accrued and other liabilities          
License agreements          
Accrued and other liabilities   $ 1,000   $ 1,000 $ 100
Minimum | MacroGenics          
License agreements          
Royalty payments on future global net sales (as a percent)   15.00%      
Maximum | MacroGenics          
License agreements          
Royalty payments on future global net sales (as a percent)   24.00%      
Development and Regulatory Milestones | MacroGenics          
License agreements          
Milestone payment made under license agreement       65,000  
Development and Regulatory Milestones | Maximum | MacroGenics          
License agreements          
Additional milestone payments under the license agreement   $ 355,000   355,000  
Sales and Commercial Milestones | Maximum | MacroGenics          
License agreements          
Additional milestone payments under the license agreement   $ 330,000   $ 330,000