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License Agreements - Lilly (Details) - USD ($) $ in Thousands	1 Months Ended			3 Months Ended		6 Months Ended		139 Months Ended
	May 31, 2019	Mar. 31, 2016	Dec. 31, 2009	Jun. 30, 2021	Jun. 30, 2020	Jun. 30, 2021	Jun. 30, 2020	Jun. 30, 2021
License agreements
Research and Development Expense				$ 343,511	$ 286,601	$ 650,407	$ 1,371,888
Revenues				705,709	688,043	1,310,427	1,256,550
Product royalty revenues
License agreements
Revenues				120,559	92,753	$ 220,466	174,533
Eli Lilly
License agreements
Upfront payment received under license agreement			$ 90,000
Eli Lilly | Phase IIB
License agreements
Associated future global development costs from the initiation of a Phase IIb trial, if elected to co-develop (as a percentage)						30.00%
Associated future royalty payments from the initiation of a Phase IIb trial, if elected to not co-develop, percentage						20.00%
Eli Lilly | Pre-specified Events | Maximum
License agreements
Upfront and immediate milestone payment to be received under license agreement			665,000
Eli Lilly | Development Milestones
License agreements
Amount recognized and received for the achievement of a predefined milestone								$ 149,000
Eli Lilly | Development Milestones | Maximum
License agreements
Upfront and immediate milestone payment to be received under license agreement			150,000
Eli Lilly | Regulatory Milestones
License agreements
Amount recognized and received for the achievement of a predefined milestone								$ 265,000
Eli Lilly | Regulatory Milestones | Maximum
License agreements
Upfront and immediate milestone payment to be received under license agreement			365,000
Eli Lilly | Sales and Commercial Milestones | Maximum
License agreements
Upfront and immediate milestone payment to be received under license agreement			$ 150,000
Eli Lilly | Product royalty revenues
License agreements
Revenues				36,000	25,800	$ 68,300	51,300
Eli Lilly | GVHD
License agreements
Upfront payment under license agreement		$ 35,000
Additional milestone payments under the license agreement		$ 40,000
Eli Lilly | GVHD | Regulatory Milestones
License agreements
Milestone payment made under license agreement	$ 20,000
Eli Lilly | Milestone revenues
License agreements
Revenues				$ 0	$ 0	$ 0	$ 0

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