XML 60 R49.htm IDEA: XBRL DOCUMENT v3.21.2
License Agreements - Agenus (Details)
$ / shares in Units, $ in Thousands, shares in Millions
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Feb. 14, 2017
USD ($)
$ / shares
Feb. 01, 2017
USD ($)
$ / shares
shares
Feb. 28, 2017
USD ($)
Nov. 30, 2015
item
Jan. 31, 2015
USD ($)
item
Jun. 30, 2021
USD ($)
$ / shares
shares
Mar. 31, 2021
USD ($)
$ / shares
shares
Sep. 30, 2020
USD ($)
$ / shares
shares
Jun. 30, 2020
USD ($)
$ / shares
shares
Jun. 30, 2021
USD ($)
$ / shares
Jun. 30, 2020
USD ($)
$ / shares
Dec. 31, 2017
USD ($)
Dec. 31, 2020
USD ($)
License agreements                          
Long term investments           $ 220,691       $ 220,691     $ 222,301
Unrealized gain (loss) on long term investments           26,765     $ 72,274 (944) $ 24,142    
Research and development expense           343,511     $ 286,601 $ 650,407 1,371,888    
Agenus                          
License agreements                          
Number of program targets | item       3 4                
Royalty payments on future global net sales (as a percent)                   15.00%      
Upfront payment under license agreement         $ 60,000                
Period of notice for termination of license agreement     12 months                    
Agenus | Development, Regulatory and Commercialization Milestones | Minimum                          
License agreements                          
Royalty payments on future global net sales (as a percent)                   6.00%      
Agenus | Development, Regulatory and Commercialization Milestones | Maximum                          
License agreements                          
Royalty payments on future global net sales (as a percent)                   12.00%      
Additional milestone payments under the license agreement     $ 500,000                    
Agenus | Development Milestones                          
License agreements                          
Upfront payment under license agreement                       $ 20,000  
Additional milestone payments under the license agreement             $ 10,000            
Agenus                          
License agreements                          
Long term investments           $ 67,300       $ 67,300     44,700
Ownership percentage (as a percent) 18.00%         6.00%       6.00%      
Shares divested (in shares) | shares           1.6 0.2 2.5 1.2        
Share price (per share) | $ / shares             $ 5.45            
Gross proceeds from sale of stock           $ 8,200 $ 1,100 $ 12,700 $ 4,500        
Unrealized gain (loss) on long term investments           37,800     26,200 $ 31,900 (2,700)    
Research and development expense           200     $ 200 700 $ 300    
Agenus | Accrued and other liabilities                          
License agreements                          
Accrued and other liabilities           $ 600       $ 600     $ 500
Agenus | Minimum                          
License agreements                          
Share price (per share) | $ / shares           $ 4.59   $ 4.28 $ 3.57 $ 4.59 $ 3.57    
Agenus | Maximum                          
License agreements                          
Share price (per share) | $ / shares           $ 5.41   $ 5.25 $ 4.21 $ 5.41 $ 4.21    
Agenus | Stock purchase agreement                          
License agreements                          
Total consideration paid $ 60,000                        
Purchase of common stock under Stock Purchase Agreement (in shares ) | shares   10.0                      
Purchase price of common stock   $ 60,000                      
Per share price | $ / shares $ 4.40 $ 6.00                      
Discount for lack of marketability $ 4,500                        
Fair value of shares on the issuance date $ 39,500                        
Long term investments                       39,500  
Research and development expense                       $ 20,500