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License Agreements - MacroGenics (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
Dec. 31, 2017
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Dec. 31, 2020
License agreements            
Research and development   $ 343,511 $ 286,601 $ 650,407 $ 1,371,888  
MacroGenics            
License agreements            
Upfront payment under license agreement $ 150,000          
Research and development   17,600 $ 16,300 31,200 $ 32,700  
MacroGenics | Accrued and other liabilities            
License agreements            
Accrued and other liabilities   $ 900   900   $ 100
Minimum | MacroGenics            
License agreements            
Royalty payments on future global net sales (as a percent) 15.00%          
Maximum | MacroGenics            
License agreements            
Royalty payments on future global net sales (as a percent) 24.00%          
Development and Regulatory Milestones | MacroGenics            
License agreements            
Milestone payment made under license agreement       $ 70,000    
Development and Regulatory Milestones | Maximum | MacroGenics            
License agreements            
Additional milestone payments under the license agreement $ 350,000          
Sales and Commercial Milestones | Maximum | MacroGenics            
License agreements            
Additional milestone payments under the license agreement $ 330,000