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Property and Equipment, net - Property and equipment, net (Details) - USD ($) $ in Thousands	Sep. 30, 2021	Dec. 31, 2020
Property and equipment, net
Property and Equipment, gross	$ 854,512	$ 703,999
Less accumulated depreciation and amortization	(167,794)	(144,374)
Property and Equipment, net	686,718	559,625
Office equipment
Property and equipment, net
Property and Equipment, gross	18,395	17,880
Laboratory equipment
Property and equipment, net
Property and Equipment, gross	103,502	86,021
Computer equipment
Property and equipment, net
Property and Equipment, gross	75,105	66,640
Land
Property and equipment, net
Property and Equipment, gross	10,379	10,671
Building and leasehold improvements
Property and equipment, net
Property and Equipment, gross	277,901	238,042
Operating lease right-of-use assets
Property and equipment, net
Property and Equipment, gross	25,544	26,816
Construction in Progress
Property and equipment, net
Property and Equipment, gross	$ 343,686	$ 257,929

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- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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