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License Agreements - Merus (Details) - USD ($) $ / shares in Units, $ in Thousands		1 Months Ended				3 Months Ended		9 Months Ended		12 Months Ended
	Jan. 23, 2017	Jan. 31, 2021	Feb. 28, 2017	Jan. 31, 2017	Dec. 31, 2016	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020	Dec. 31, 2017	Dec. 31, 2020
License agreements
Long term investments						$ 192,096		$ 192,096			$ 222,301
Research and development expense						334,945	$ 438,109	985,352	$ 1,809,997
Unrealized gain (loss) on long term investments						(27,450)	(13,207)	(28,394)	10,935
Total revenues						812,987	620,643	2,123,414	1,877,193
Net income (loss)								384,730	(445,547)
Current assets						2,923,797		2,923,797			2,359,894
Current liabilities						742,712		742,712			631,195
Merus
License agreements
Associated future global development costs , if elected to co-develop (as a percent)				35.00%
Upfront payment under license agreement			$ 120,000
Research and development expense						3,100	1,800	10,900	6,000
Merus | Accrued and other liabilities
License agreements
Accrued and other liabilities						1,600		1,600			1,600
Merus | U.S.
License agreements
Profit sharing (as a percent)				50.00%
Percentage of profit (losses)				50.00%
Merus | Minimum
License agreements
Royalty payments on future global net sales (as a percent)				6.00%
Merus | Minimum | U.S.
License agreements
Royalty payments on future global net sales (as a percent)				6.00%
Merus | Minimum | Non-U.S.
License agreements
Royalty payments on future global net sales (as a percent)				6.00%
Merus | Maximum
License agreements
Royalty payments on future global net sales (as a percent)				10.00%
Percentage of reverse royalty				4.00%
Merus | Maximum | U.S.
License agreements
Royalty payments on future global net sales (as a percent)				10.00%
Percentage of additional royalties				4.00%
Merus | Maximum | Non-U.S.
License agreements
Royalty payments on future global net sales (as a percent)				10.00%
Merus | Maximum | Development and Regulatory Milestones
License agreements
Additional milestone payments under the license agreement				$ 100,000
Merus | Maximum | Sales and Commercial Milestones
License agreements
Additional milestone payments under the license agreement				$ 250,000
Merus
License agreements
Per share price of common stock	$ 24.50
Discount for lack of marketability	$ 5,600
Fair value of shares on the issuance date	72,800
Total consideration paid	80,000
Long term investments	$ 72,800
Research and development expense										$ 7,200
Fair market value of our long term investments						$ 78,100		$ 78,100			$ 56,100
Ownership percentage (as a percent)						9.00%		9.00%
Unrealized gain (loss) on long term investments						$ 3,300	$ (13,100)	$ 13,300	$ (6,700)
Merus | IPO
License agreements
Common shares purchased (in shares)		350,000
Number of shares in underwritten public offering (in shares)		4,848,485
Per share price		$ 24.75
Value of shares acquired		$ 8,700
Merus | Stock purchase agreement
License agreements
Purchase of common stock under Stock Purchase Agreement (in shares )					3,200,000
Purchase price of common stock					$ 80,000
Per share price					$ 25.00

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