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License Agreements - MacroGenics (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Oct. 31, 2017
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Dec. 31, 2020
Dec. 31, 2017
License agreements              
Research and development   $ 334,945 $ 438,109 $ 985,352 $ 1,809,997    
MacroGenics              
License agreements              
Upfront payment under license agreement $ 150,000            
Research and development   17,800 $ 10,600 49,000 $ 43,300    
MacroGenics | Accrued and other liabilities              
License agreements              
Accrued and other liabilities   $ 0   0   $ 100  
Minimum | MacroGenics              
License agreements              
Royalty payments on future global net sales (as a percent) 15.00%            
Maximum | MacroGenics              
License agreements              
Royalty payments on future global net sales (as a percent) 24.00%            
Development and Regulatory Milestones | MacroGenics              
License agreements              
Milestone payment made under license agreement       $ 70,000      
Development and Regulatory Milestones | Maximum | MacroGenics              
License agreements              
Additional milestone payments under the license agreement $ 350,000            
Sales and Commercial Milestones | Maximum | MacroGenics              
License agreements              
Additional milestone payments under the license agreement             $ 330,000