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License Agreements - MorphoSys (Details) - USD ($) $ / shares in Units, $ in Thousands | 1 Months Ended | 12 Months Ended |
--- | --- | --- | ---
Mar. 31, 2019 | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019 | Jan. 31, 2020
Long term investments |  | $ 221,266 | $ 222,301 |  |
Research and development expense |  | 1,458,179 | 2,215,942 | $ 1,154,111 |
Unrealized (loss) gain on long term investments |  | (24,072) | 10,426 | $ 34,458 |
Collaboration loss sharing |  | 37,019 | 42,801 |  |
ADSs |  |  |  |  |
Ownership percentage (as a percent) |  |  |  |  | 0.25%
Equity Method Investment, Aggregate Cost |  |  |  |  | $ 150,000
Per share price |  |  |  |  | $ 41.33
Long term investments |  | $ 34,200 | 102,900 |  |
MorphoSys AG |  |  |  |  |
Upfront payment under license agreement | $ 750,000 |  |  |  |
Ownership percentage (as a percent) |  | 0.03% |  |  |
Research and development expense |  | $ 77,000 | 88,200 |  |
Unrealized (loss) gain on long term investments |  | $ (68,700) | $ 7,400 |  |
Profit (loss) sharing ratio |  | 50.00% | 50.00% |  |
Collaboration loss sharing |  | $ 37,000 | $ 42,800 |  |
Associated future global development costs from the initiation of a Phase IIb trial, if elected to co-develop (as a percentage) |  | 0.55% |  |  |
Accrued and other liabilities |  | $ 21,500 | $ 54,200 |  |
MorphoSys AG | Development and Regulatory Milestones | Maximum |  |  |  |  |
Additional milestone payments under the license agreement |  |  |  |  | $ 740,000
MorphoSys AG | Commercialization Milestones | Maximum |  |  |  |  |
Additional milestone payments under the license agreement |  |  |  |  | $ 315,000
MorphoSys AG | MorphoSys AG |  |  |  |  |
Funding of future development costs (as a percent) |  | 0.45% |  |  |
MorphoSys AG | Incyte |  |  |  |  |
Funding of future development costs (as a percent) |  | 0.55% |  |  |

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