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Concentrations of Credit Risk and Current Expected Credit Losses (Details)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Sales Revenue Goods Services Net [Member] | Customer Concentration Risk [Member] | Customer A [Member]
Concentration of risk
Percentage of concentration risk	18.00%	20.00%	20.00%
Sales Revenue Goods Services Net [Member] | Customer Concentration Risk [Member] | Customer B [Member]
Concentration of risk
Percentage of concentration risk	12.00%	13.00%	13.00%
Sales Revenue Goods Services Net [Member] | Customer Concentration Risk [Member] | Customer C [Member]
Concentration of risk
Percentage of concentration risk	18.00%	17.00%	16.00%
Sales Revenue Goods Services Net [Member] | Customer Concentration Risk [Member] | Customer D [Member]
Concentration of risk
Percentage of concentration risk	11.00%	10.00%	8.00%
Accounts Receivable [Member] | Credit Concentration Risk [Member] | Collaboration Partner A, B, C and D
Concentration of risk
Percentage of concentration risk	36.00%	42.00%
Accounts Receivable [Member] | Credit Concentration Risk [Member] | Customer A, B, C D, and E
Concentration of risk
Percentage of concentration risk	31.00%	33.00%

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