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Revenues (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021
Revenues |  |  |  |
Total revenues | $ 823,303 | $ 812,987 | $ 2,467,935 | $ 2,123,414
Product revenues, net |  |  |  |
Revenues |  |  |  |
Total revenues | 713,010 | 594,013 | 1,982,682 | 1,673,974
JAKAFI |  |  |  |
Revenues |  |  |  |
Total revenues | 619,595 | 547,373 | 1,761,732 | 1,542,138
ICLUSIG |  |  |  |
Revenues |  |  |  |
Total revenues | 25,929 | 28,522 | 78,222 | 82,356
PEMAZYRE |  |  |  |
Revenues |  |  |  |
Total revenues | 23,414 | 17,562 | 60,429 | 48,924
MINJUVI |  |  |  |
Revenues |  |  |  |
Total revenues | 5,932 | 556 | 14,845 | 556
OPZELURA |  |  |  |
Revenues |  |  |  |
Total revenues | 38,140 | 0 | 67,454 | 0
Product royalty revenues |  |  |  |
Revenues |  |  |  |
Total revenues | 110,293 | 183,974 | 350,253 | 404,440
JAKAVI Royalty Revenues |  |  |  |
Revenues |  |  |  |
Total revenues | 85,808 | 94,655 | 240,386 | 242,295
OLUMIANT Royalty Revenues |  |  |  |
Revenues |  |  |  |
Total revenues | 20,371 | 86,572 | 98,689 | 154,875
TABRECTA Royalty Revenues |  |  |  |
Revenues |  |  |  |
Total revenues | 4,114 | 2,747 | 11,178 | 7,270
Milestone and contract revenues |  |  |  |
Revenues |  |  |  |
Total revenues | $ 0 | $ 35,000 | $ 135,000 | $ 45,000

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