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Accrued and Other Current Liabilities (Tables)

9 Months Ended

Sep. 30, 2022

Payables and Accruals [Abstract]

Schedule of accrued and other current liabilities

Accrued and other current liabilities consisted of the following (in thousands):

			September 30, 2022						December 31, 2021
Royalties			$	248,455					$	168,412
Clinical related costs			152,764						109,486
Sales allowances			186,112						136,541
Sales and marketing			31,001						35,750
Construction in progress			8,836						27,098
Operating lease liabilities			8,492						10,554
Other current liabilities			64,154						45,754
Total accrued and other current liabilities			$	699,814					$	533,595

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Tabular disclosure of the components of accrued liabilities.

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