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Inventory (Details) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2022
Dec. 31, 2021
Raw materials $ 32,289 $ 1,275
Work-in-process 35,465 39,895
Finished goods 33,379 15,768
Total inventory 101,133 56,938
Inventories - current 45,869 27,904
Inventories-noncurrent 55,264 $ 29,034
Inventory incurred prior to FDA approval $ 56,800  
Maximum    
Period of lower average per unit cost of materials 28 months