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License Agreements - Lilly (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended 154 Months Ended
Jun. 30, 2022
Mar. 31, 2022
May 31, 2019
Dec. 31, 2009
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Jun. 30, 2016
License Agreements                    
Revenues         $ 823,303 $ 812,987 $ 2,467,935 $ 2,123,414    
OLUMIANT Royalty Revenues                    
License Agreements                    
Revenues         20,371 86,572 98,689 154,875    
Eli Lilly | Development Milestones                    
License Agreements                    
Amount recognized and received for the achievement of a predefined milestone                 $ 149,000  
Eli Lilly | Development Milestones | Maximum                    
License Agreements                    
Upfront and immediate milestone payment to be received under license agreement       $ 150,000            
Eli Lilly | Regulatory Milestones                    
License Agreements                    
Amount recognized and received for the achievement of a predefined milestone                 335,000  
Eli Lilly | Regulatory Milestones | Maximum                    
License Agreements                    
Upfront and immediate milestone payment to be received under license agreement       365,000            
Eli Lilly | Commercialization Milestones                    
License Agreements                    
Amount recognized and received for the achievement of a predefined milestone                 $ 50,000  
Eli Lilly | Commercialization Milestones | Maximum                    
License Agreements                    
Upfront and immediate milestone payment to be received under license agreement       $ 150,000            
Eli Lilly | OLUMIANT                    
License Agreements                    
Revenues         0   70,000      
Eli Lilly | OLUMIANT | Regulatory Milestones | UNITED STATES                    
License Agreements                    
Amount recognized and received for the achievement of a predefined milestone $ 40,000                  
Eli Lilly | OLUMIANT | Regulatory Milestones | Europe                    
License Agreements                    
Amount recognized and received for the achievement of a predefined milestone 20,000                  
Eli Lilly | OLUMIANT | Regulatory Milestones | JAPAN                    
License Agreements                    
Amount recognized and received for the achievement of a predefined milestone $ 10,000                  
Eli Lilly | OLUMIANT Royalty Revenues | Non-US                    
License Agreements                    
Royalties payable on net sales         $ 20,400 $ 86,600 $ 98,700 $ 154,900    
Eli Lilly | GVHD | Regulatory Milestones                    
License Agreements                    
Milestone payment made under license agreement     $ 20,000              
Eli Lilly | GVHD | Regulatory Milestones | Europe                    
License Agreements                    
Milestone payment made under license agreement   $ 20,000                
Eli Lilly | GVHD | Regulatory Milestones | Maximum                    
License Agreements                    
Additional milestone payments under the license agreement                   $ 40,000