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License Agreements - Merus (Details) $ / shares in Units, $ in Thousands	1 Months Ended			3 Months Ended		9 Months Ended		12 Months Ended	70 Months Ended
	Jan. 31, 2022 item	Jan. 31, 2021 USD ($) $ / shares shares	Dec. 31, 2016 USD ($) item $ / shares	Sep. 30, 2022 USD ($)	Sep. 30, 2021 USD ($)	Sep. 30, 2022 USD ($)	Sep. 30, 2021 USD ($)	Dec. 31, 2016 USD ($) $ / shares shares	Sep. 30, 2022 USD ($)	Dec. 31, 2021 USD ($)
License Agreements
Unrealized gain (loss) on long term investments				$ (660)	$ (27,450)	$ (72,142)	$ (28,394)
Merus
License Agreements
Fair market value of our long term investments				$ 71,100		$ 71,100			$ 71,100	$ 112,900
Ownership percentage (as a percent)				8.00%		8.00%			8.00%
Unrealized gain (loss) on long term investments				$ (9,300)	$ 3,300	$ (41,800)	$ 13,300
Merus | IPO
License Agreements
Per share price (In USD per share) | $ / shares		$ 24.75
Common shares purchased (in shares) | shares		350,000
Number of shares in underwritten public offering (in shares) | shares		4,848,485
Value of shares acquired		$ 8,700
Merus
License Agreements
Number of independent programs | item			10
Number of additional preclinical discovery programs | item	10
Number of programs under the resulting products are co-funded for development | item	2
Associated future global development costs , if elected to co-develop (as a percent)	35.00%
Milestone payment made under license agreement									$ 3,000
Merus | UNITED STATES
License Agreements
Profit sharing (as a percent)									50.00%
Percentage of profit (losses)									50.00%
Merus | Minimum
License Agreements
Royalty payments on future global net sales (as a percent)									6.00%
Merus | Minimum | Non-US
License Agreements
Royalty payments on future global net sales (as a percent)									6.00%
Merus | Maximum
License Agreements
Royalty payments on future global net sales (as a percent)									10.00%
Merus | Maximum | UNITED STATES
License Agreements
Royalty payments on future global net sales (as a percent)									4.00%
Merus | Maximum | Non-US
License Agreements
Royalty payments on future global net sales (as a percent)									10.00%
Merus | Maximum | Development and Regulatory Milestones
License Agreements
Additional milestone payments under the license agreement				100,000		100,000			$ 100,000
Merus | Maximum | Commercialization Milestones
License Agreements
Additional milestone payments under the license agreement				$ 250,000		$ 250,000			$ 250,000
Stock purchase agreement | Merus
License Agreements
Purchase of common stock under Stock Purchase Agreement (in shares ) | shares								3,200,000
Purchase price of common stock			$ 80,000					$ 80,000
Per share price (In USD per share) | $ / shares			$ 25.00					$ 25.00

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