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License Agreements - Calithera (Details) $ / shares in Units, $ in Thousands	1 Months Ended		3 Months Ended		9 Months Ended		12 Months Ended
	Jun. 30, 2022 shares	Jan. 31, 2017 USD ($) $ / shares	Sep. 30, 2022 USD ($)	Sep. 30, 2021 USD ($)	Sep. 30, 2022 USD ($)	Sep. 30, 2021 USD ($)	Dec. 31, 2017 shares	Dec. 31, 2021 USD ($)
License Agreements
Fair market long term investments			$ 149,124		$ 149,124			$ 221,266
Unrealized gain (loss) on long term investments			(660)	$ (27,450)	(72,142)	$ (28,394)
Calithera
License Agreements
Fair market long term investments			300		300			$ 1,100
Calithera | Other Comprehensive Income (Loss)
License Agreements
Unrealized gain (loss) on long term investments			$ 0	$ 200	$ (900)	$ (4,600)
Calithera
License Agreements
Funding of future development costs (as a percent)		70.00%
Stock purchase agreement | Calithera
License Agreements
Purchase of common stock under Stock Purchase Agreement (in shares ) | shares							1,700,000
Purchase price of common stock		$ 8,000
Per share price (In USD per share) | $ / shares		$ 4.65
Effected stock split (as a percent)	0.05
Ownership (in shares) | shares	86,021

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- Definition

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Represents the purchase of common stock under Stock Purchase Agreement.

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Amount of unrealized gain (loss) on investment in equity security measured at fair value with change in fair value recognized in net income (FV-NI).

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The total amount of investments that are intended to be held for an extended period of time (longer than one operating cycle).

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