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License Agreements - MacroGenics (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended 57 Months Ended
Jul. 31, 2022
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Jun. 30, 2022
Dec. 31, 2021
License Agreements              
Research and development   $ 384,007 $ 334,945 $ 1,084,576 $ 985,352    
MacroGenics              
License Agreements              
Research and development   41,600 $ 17,800 69,900 $ 49,000    
MacroGenics | Accrued Liabilities              
License Agreements              
Accrued and other liabilities   2,700   2,700     $ 700
MacroGenics | Minimum              
License Agreements              
Royalty payments on future global net sales (as a percent)           15.00%  
MacroGenics | Maximum              
License Agreements              
Royalty payments on future global net sales (as a percent)           24.00%  
MacroGenics | Development and Regulatory Milestones | Maximum              
License Agreements              
Additional milestone payments under the license agreement   $ 335,000   $ 335,000      
MacroGenics | Development Milestones              
License Agreements              
Milestone payment made under license agreement $ 30,000         $ 100,000  
MacroGenics | Commercialization Milestones | Maximum              
License Agreements              
Additional milestone payments under the license agreement           $ 330,000