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License Agreements - Syros (Details) $ / shares in Units, $ in Thousands	1 Months Ended		3 Months Ended		9 Months Ended		12 Months Ended
	Jun. 30, 2022	Jan. 31, 2018 USD ($) item	Sep. 30, 2022 USD ($) shares	Sep. 30, 2021 USD ($)	Sep. 30, 2022 USD ($) shares	Sep. 30, 2021 USD ($)	Dec. 31, 2018 USD ($) $ / shares shares	Dec. 31, 2021 USD ($)
License Agreements
Fair market long term investments			$ 149,124		$ 149,124			$ 221,266
Unrealized gain (loss) on long term investments			(660)	$ (27,450)	(72,142)	$ (28,394)
Syros Pharmaceuticals, Inc.
License Agreements
Fair market long term investments			600		600			$ 3,100
Unrealized gain (loss) on long term investments			$ (300)	$ (900)	$ (2,500)	$ (6,000)
Syros Pharmaceuticals, Inc.
License Agreements
Number of program targets | item		7
Syros Pharmaceuticals, Inc. | Maximum
License Agreements
Target selection and option exercise fee payment		$ 54,000
Syros Pharmaceuticals, Inc. | Development and Regulatory Milestones | Maximum
License Agreements
Additional milestone payments under the license agreement		50,000
Syros Pharmaceuticals, Inc. | Commercialization Milestones | Maximum
License Agreements
Additional milestone payments under the license agreement		$ 65,000
Stock purchase agreement | Syros Pharmaceuticals, Inc.
License Agreements
Purchase price of common stock							$ 10,000
Per share price (In USD per share) | $ / shares							$ 12.61
Ownership (in shares) | shares			93,753		93,753
Effected stock split (as a percent)	0.01
Stock purchase agreement | Syros Pharmaceuticals, Inc. | Pre September 2022 -Stock Split Shares
License Agreements
Purchase of common stock under Stock Purchase Agreement (in shares ) | shares							800,000
Amended stock purchase agreement | Syros Pharmaceuticals, Inc.
License Agreements
Purchase price of common stock							$ 1,400
Per share price (In USD per share) | $ / shares							$ 9.55
Amended stock purchase agreement | Syros Pharmaceuticals, Inc. | Pre September 2022 -Stock Split Shares
License Agreements
Purchase of common stock under Stock Purchase Agreement (in shares ) | shares							100,000

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