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Stock Compensation - Narrative (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Stock compensation
Stock compensation expense	$ 45.4	$ 42.7	$ 135.7	$ 134.8
Dividend yield (as a percent)			0.00%
Assumed annualized forfeiture rate (as a percent)			5.00%
Share-based Payment Arrangement, Option
Stock compensation
Stock option grant term			10 years
Vesting period			4 years
Percentage of units vesting at the end of each calendar year (as a percent)			25.00%
Unrecognized compensation
Unrecognized compensation cost for nonvested option (in dollars)	51.2		$ 51.2
Vesting period of recognition of the unrecognized compensation cost of nonvested awards			1 year 1 month 6 days
Share-based Payment Arrangement, Option | Share-based Payment Arrangement, Tranche One
Stock compensation
Vesting period			1 year
Share-based Payment Arrangement, Option | Share-based Payment Arrangement, Tranche Two
Stock compensation
Vesting period			36 months
Restricted Stock Units (RSUs)
Stock compensation
Vesting period			4 years
Percentage of units vesting at the end of each calendar year (as a percent)			25.00%
Number of shares awarded for each RSU (in shares)			1
Unrecognized compensation
Unrecognized compensation cost for nonvested option (in dollars)	235.5		$ 235.5
Vesting period of recognition of the unrecognized compensation cost of nonvested awards			2 years
Performance Shares
Stock compensation
Stock compensation expense	3.2	1.7	$ 5.1	5.0
Unrecognized compensation
Unrecognized compensation cost for nonvested option (in dollars)	19.6		$ 19.6
Vesting period of recognition of the unrecognized compensation cost of nonvested awards			2 years 2 months 12 days
Performance Shares | Minimum
Stock compensation
Vesting period			3 years
Performance Shares | Maximum
Stock compensation
Vesting period			4 years
Research and Development Expense
Stock compensation
Stock compensation expense	25.8	26.3	$ 80.2	84.2
Selling, General and Administrative Expenses
Stock compensation
Stock compensation expense	18.9	15.9	53.5	49.5
Cost of Sales
Stock compensation
Stock compensation expense	$ 0.7	$ 0.5	$ 2.0	$ 1.1

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