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Stock Compensation - Option activity under the 2010 stock plan (Details) - Share-based Payment Arrangement, Option - $ / shares
9 Months Ended
Sep. 30, 2022
Dec. 31, 2021
Option Activity Shares    
Outstanding at the beginning of the period (in shares) 12,763,460  
Options granted (in shares) 1,755,963  
Options exercised (in shares) (477,371)  
Options cancelled (in shares) (989,465)  
Outstanding at the end of the period (in shares) 13,052,587  
Stock Options Weighted Average Price    
Exercise prices of options outstanding (in USD per share) $ 87.41 $ 88.39
Granted (in USD per share) 75.32  
Exercised (in USD per share) 66.69  
Cancelled (in USD per share) $ 88.60